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Cc2d2b coiled-coil and C2 domain containing 2B [ Mus musculus (house mouse) ]

Gene ID: 668310, updated on 29-Jul-2024

Summary

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Official Symbol
Cc2d2bprovided by MGI
Official Full Name
coiled-coil and C2 domain containing 2Bprovided by MGI
Primary source
MGI:MGI:3645359
See related
Ensembl:ENSMUSG00000108929 AllianceGenome:MGI:3645359
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm338; EG668310
Summary
Predicted to be involved in non-motile cilium assembly and protein localization to ciliary transition zone. Predicted to be active in ciliary transition zone. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 4.6) and liver E14 (RPKM 0.2) See more
Orthologs
human all
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Genomic context

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See Cc2d2b in Genome Data Viewer
Location:
19 C3; 19 34.26 cM
Exon count:
36
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (40737197..40818227)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (40748753..40829778)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene ectonucleoside triphosphate diphosphohydrolase 1 Neighboring gene predicted gene, 54044 Neighboring gene predicted gene, 41846 Neighboring gene STARR-seq mESC enhancer starr_46135 Neighboring gene STARR-positive B cell enhancer mm9_chr19:40895901-40896202 Neighboring gene predicted gene, 33482 Neighboring gene cyclin J Neighboring gene RIKEN cDNA E030044B06 gene Neighboring gene STARR-seq mESC enhancer starr_46136 Neighboring gene predicted gene, 57494

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in non-motile cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein localization to ciliary transition zone IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in ciliary transition zone IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
protein CC2D2B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001376940.1 → NP_001363869.1  protein CC2D2B

    Status: VALIDATED

    Source sequence(s)
    AC117253, AC166063, AC169520
    UniProtKB/TrEMBL
    A0A286YDU8
    Related
    ENSMUSP00000153384.2, ENSMUST00000224596.2
    Conserved Domains (3) summary
    pfam15625
    Location:465 → 632
    CC2D2AN-C2; CC2D2A N-terminal C2 domain
    pfam17661
    Location:23 → 260
    DUF5523; Family of unknown function (DUF5523)
    cl14603
    Location:907 → 940
    C2; C2 domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    40737197..40818227
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011247419.3 → XP_011245721.2  protein CC2D2B isoform X1

    UniProtKB/TrEMBL
    A0A286YDU8
    Conserved Domains (3) summary
    pfam15625
    Location:504 → 671
    CC2D2AN-C2; CC2D2A N-terminal C2 domain
    pfam17661
    Location:23 → 260
    DUF5523; Family of unknown function (DUF5523)
    cl14603
    Location:946 → 979
    C2; C2 domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Chemical Information
Molecular Biology Databases
Research Materials