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Fbxw28 F-box and WD-40 domain protein 28 [ Mus musculus (house mouse) ]

Gene ID: 668758, updated on 9-Dec-2024

Summary

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Official Symbol
Fbxw28provided by MGI
Official Full Name
F-box and WD-40 domain protein 28provided by MGI
Primary source
MGI:MGI:3779847
See related
Ensembl:ENSMUSG00000054087 AllianceGenome:MGI:3779847
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm9337
Summary
Predicted to be active in cytoplasm. Orthologous to human FBXW12 (F-box and WD repeat domain containing 12). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Restricted expression toward ovary adult (RPKM 1.4) See more
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Genomic context

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See Fbxw28 in Genome Data Viewer
Location:
9 F2; 9 59.64 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (109151862..109168727, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (109322794..109339659, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene F-box and WD-40 domain protein 14 Neighboring gene predicted gene, 22821 Neighboring gene predicted gene, 25484 Neighboring gene predicted gene, 24641

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  2. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  3. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
  4. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article
  5. Functional annotation of a full-length mouse cDNA collection. Kawai J, et al. Nature, 2001 Feb 8. PMID 11217851

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
F-box and WD-40 domain protein 28

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001177419.1 → NP_001170890.1  F-box and WD-40 domain protein 28 isoform 1

    See identical proteins and their annotated locations for NP_001170890.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the shorter isoform (1).
    Source sequence(s)
    AC164438, AK143322
    Consensus CDS
    CCDS52932.1
    UniProtKB/TrEMBL
    B9EHJ2, Q3UPQ4
    Related
    ENSMUSP00000107671.3, ENSMUST00000112040.9
    Conserved Domains (1) summary
    pfam12937
    Location:4 → 48
    F-box-like; F-box-like

  2. NM_001177420.1 → NP_001170891.1  F-box and WD-40 domain protein 28 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate terminal exon and differs in the 3' coding region and 3' UTR compared to variant 1. The resulting protein (isoform 2) has a different, longer C-terminus compared to isoform 1.
    Source sequence(s)
    AC164438, BC084592
    Consensus CDS
    CCDS52933.1
    UniProtKB/TrEMBL
    B9EHJ2, E9Q8A4
    Related
    ENSMUSP00000107670.3, ENSMUST00000112039.7
    Conserved Domains (1) summary
    pfam12937
    Location:4 → 48
    F-box-like; F-box-like

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    109151862..109168727 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006512211.2 → XP_006512274.1  F-box and WD-40 domain protein 28 isoform X1

    UniProtKB/TrEMBL
    A0A0G2JFZ2, B7ZN94
    Related
    ENSMUSP00000143361.2, ENSMUST00000200156.5
    Conserved Domains (1) summary
    pfam12937
    Location:4 → 46
    F-box-like
Nucleotide Protein Strain
Heading Accession and Version

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