Rpl14 ribosomal protein L14 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Rpl14provided by MGI
Official Full Name: ribosomal protein L14provided by MGI
Primary source: MGI:MGI:1914365
See related: Ensembl:ENSMUSG00000025794 AllianceGenome:MGI:1914365
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: L14; CTG-B33; CAG-ISL-7; 3100001N19Rik
Summary: Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in rRNA processing and ribosomal large subunit biogenesis. Predicted to be located in cytosolic ribosome. Predicted to be part of cytosolic large ribosomal subunit. Predicted to be active in postsynaptic density. Is expressed in several structures, including neural retina; nucleus pulposus; pancreas epithelium; and ureter. Human ortholog(s) of this gene implicated in systemic lupus erythematosus. Orthologous to human RPL14 (ribosomal protein L14). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in liver E14 (RPKM 295.9), bladder adult (RPKM 264.8) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 9 F4; 9 71.74 cM

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	9	NC_000075.7 (120400579..120403724)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	9	NC_000075.6 (120571517..120574653)

Chromosome 9 - NC_000075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH124609 (e-PCR)
- UniSTS:161431

RH126508 (e-PCR)
- UniSTS:209653

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of ribosome	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of ribosome	IDA Inferred from Direct Assay more info	PubMed
enables structural constituent of ribosome	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in cytoplasmic translation	NAS Non-traceable Author Statement more info	PubMed
involved_in rRNA processing	ISO Inferred from Sequence Orthology more info
involved_in ribosomal large subunit biogenesis	IBA Inferred from Biological aspect of Ancestor more info
involved_in ribosomal large subunit biogenesis	ISO Inferred from Sequence Orthology more info
involved_in translation	IEA Inferred from Electronic Annotation more info
involved_in translation at postsynapse	NAS Non-traceable Author Statement more info	PubMed
involved_in translation at presynapse	NAS Non-traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytosol	TAS Traceable Author Statement more info
part_of cytosolic large ribosomal subunit	IBA Inferred from Biological aspect of Ancestor more info
part_of cytosolic large ribosomal subunit	IDA Inferred from Direct Assay more info	PubMed
part_of cytosolic large ribosomal subunit	IPI Inferred from Physical Interaction more info	PubMed
part_of cytosolic large ribosomal subunit	ISO Inferred from Sequence Orthology more info
located_in cytosolic ribosome	ISO Inferred from Sequence Orthology more info
is_active_in postsynapse	NAS Non-traceable Author Statement more info	PubMed
is_active_in postsynaptic density	ISO Inferred from Sequence Orthology more info
is_active_in presynapse	NAS Non-traceable Author Statement more info	PubMed
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
is_active_in ribosome	NAS Non-traceable Author Statement more info	PubMed
is_active_in synapse	EXP Inferred from Experiment more info	PubMed
is_active_in synapse	IDA Inferred from Direct Assay more info	PubMed
located_in synapse	NAS Non-traceable Author Statement more info	PubMed

General protein information

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Preferred Names: large ribosomal subunit protein eL14

Names: 60S ribosomal protein L14

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_025974.3 → NP_080250.1 large ribosomal subunit protein eL14

See identical proteins and their annotated locations for NP_080250.1

Status: VALIDATED

Source sequence(s)

AC137127

Consensus CDS

CCDS40809.1

UniProtKB/Swiss-Prot

Q9CR57, Q9D8Q1

Related

ENSMUSP00000131489.2, ENSMUST00000165532.3

Conserved Domains (2) summary

cd06088
Location:7 → 81

KOW_RPL14; KOW motif of Ribosomal Protein L14

pfam01929
Location:47 → 120

Ribosomal_L14e; Ribosomal protein L14