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1700093K21Rik RIKEN cDNA 1700093K21 gene [ Mus musculus (house mouse) ]

Gene ID: 67358, updated on 9-Aug-2024

Summary

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Official Symbol
1700093K21Rikprovided by MGI
Official Full Name
RIKEN cDNA 1700093K21 geneprovided by MGI
Primary source
MGI:MGI:1914608
See related
Ensembl:ENSMUSG00000020286 AllianceGenome:MGI:1914608
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
b2b3025Clo
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Used to study visceral heterotaxy. Orthologous to human C2orf74 (chromosome 2 open reading frame 74). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 25.5) See more
Orthologs
human all
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Genomic context

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See 1700093K21Rik in Genome Data Viewer
Location:
11 A3.2; 11 14.32 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (23466203..23471915, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (23516202..23521319, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 34 Neighboring gene RIKEN cDNA 1700030C12 gene Neighboring gene STARR-positive B cell enhancer ABC_E9818 Neighboring gene predicted gene, 22753 Neighboring gene STARR-seq mESC enhancer starr_28912 Neighboring gene STARR-seq mESC enhancer starr_28914 Neighboring gene STARR-seq mESC enhancer starr_28915 Neighboring gene AHA1, activator of heat shock protein ATPase 2 Neighboring gene STARR-seq mESC enhancer starr_28916 Neighboring gene STARR-seq mESC enhancer starr_28917 Neighboring gene selenoprotein K, pseudogene 1 Neighboring gene SANT and BTB domain regulator of CSR

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The uncharacterized gene 1700093K21Rik and flanking regions are correlated with reproductive isolation in the house mouse, Mus musculus. Kass DH, et al. Mamm Genome, 2014 Jun. PMID 24549580
  2. Identification and integrative analysis of 28 novel genes specifically expressed and developmentally regulated in murine spermatogenic cells. Hong S, et al. J Biol Chem, 2005 Mar 4. PMID 15613475
  3. Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice. Miyata H, et al. Proc Natl Acad Sci U S A, 2016 Jul 12. PMID 27357688, Free PMC Article
  4. Global genetic analysis in mice unveils central role for cilia in congenital heart disease. Li Y, et al. Nature, 2015 May 28. PMID 25807483, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The 1700093K21Rik gene and flanking regions are correlated with reproductive isolation in the house mouse.
    Title: The uncharacterized gene 1700093K21Rik and flanking regions are correlated with reproductive isolation in the house mouse, Mus musculus.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Chemically induced (ENU) (1) 
  • Endonuclease-mediated (1) 
  • Targeted (1)  1 citation

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein C2orf74 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001110133.2 → NP_001103603.2  uncharacterized protein C2orf74 homolog

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has a different 5' terminal non-coding exon compared to transcript variant 1. All three variants encode the same protein.
    Source sequence(s)
    AL672049
    UniProtKB/TrEMBL
    A0A6Q6PKH4
    Related
    ENSMUSP00000131204.2, ENSMUST00000169264.8
    Conserved Domains (1) summary
    pfam15484
    Location:32 → 178
    DUF4642; Domain of unknown function (DUF4642)

  2. NM_001370913.1 → NP_001357842.1  uncharacterized protein C2orf74 homolog

    Status: VALIDATED

    Source sequence(s)
    AL672049
    UniProtKB/TrEMBL
    A0A6Q6PKH4
    Conserved Domains (1) summary
    pfam15484
    Location:32 → 178
    DUF4642; Domain of unknown function (DUF4642)

  3. NM_026105.5 → NP_080381.3  uncharacterized protein C2orf74 homolog

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the more predominant transcript variant. All three variants encode the same protein.
    Source sequence(s)
    AL672049
    UniProtKB/TrEMBL
    A0A6Q6PKH4
    Related
    ENSMUSP00000020527.7, ENSMUST00000020527.13
    Conserved Domains (1) summary
    pfam15484
    Location:32 → 178
    DUF4642; Domain of unknown function (DUF4642)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    23466203..23471915 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006514790.4 → XP_006514853.1  uncharacterized protein C2orf74 homolog isoform X1

    See identical proteins and their annotated locations for XP_006514853.1

    UniProtKB/Swiss-Prot
    Q810S2, Q9D9C4, Q9D9E2
    Conserved Domains (1) summary
    pfam15484
    Location:50 → 196
    DUF4642; Domain of unknown function (DUF4642)

  2. XM_006514789.3 → XP_006514852.1  uncharacterized protein C2orf74 homolog isoform X1

    See identical proteins and their annotated locations for XP_006514852.1

    UniProtKB/Swiss-Prot
    Q810S2, Q9D9C4, Q9D9E2
    Conserved Domains (1) summary
    pfam15484
    Location:50 → 196
    DUF4642; Domain of unknown function (DUF4642)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q810S2.1 GenPept UniProtKB/Swiss-Prot:Q810S2

Gene LinkOut

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