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Hnrnpul2 heterogeneous nuclear ribonucleoprotein U-like 2 [ Mus musculus (house mouse) ]

Gene ID: 68693, updated on 30-Apr-2024

Summary

Official Symbol
Hnrnpul2provided by MGI
Official Full Name
heterogeneous nuclear ribonucleoprotein U-like 2provided by MGI
Primary source
MGI:MGI:1915943
See related
Ensembl:ENSMUSG00000071659 AllianceGenome:MGI:1915943
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Hnrpul2; 1110031M08Rik
Summary
Predicted to enable RNA binding activity. Located in nucleus. Is expressed in central nervous system; olfactory epithelium; retina layer; and submandibular gland primordium. Orthologous to human HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U like 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 45.1), CNS E14 (RPKM 27.9) and 28 other tissues See more
Orthologs
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Genomic context

See Hnrnpul2 in Genome Data Viewer
Location:
19 A; 19 5.7 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (8796765..8811507)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (8819401..8834143)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene polymerase (RNA) II (DNA directed) polypeptide G Neighboring gene STARR-positive B cell enhancer ABC_E173 Neighboring gene zinc finger and BTB domain containing 3 Neighboring gene tetratricopeptide repeat domain 9C Neighboring gene STARR-seq mESC enhancer starr_45496 Neighboring gene BSCL2 lipid droplet biogenesis associated, seipin Neighboring gene guanine nucleotide binding protein (G protein), gamma 3 Neighboring gene LRRN4 C-terminal like

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables molecular_function ND
No biological Data available
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in alternative mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in synapse EXP
Inferred from Experiment
more info
PubMed 
is_active_in synapse IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
heterogeneous nuclear ribonucleoprotein U-like protein 2
Names
MLF1-associated nuclear protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081196.1NP_001074665.1  heterogeneous nuclear ribonucleoprotein U-like protein 2

    See identical proteins and their annotated locations for NP_001074665.1

    Status: VALIDATED

    Source sequence(s)
    AC129217
    Consensus CDS
    CCDS37908.1
    UniProtKB/Swiss-Prot
    F8VPM4, Q00PI9
    Related
    ENSMUSP00000094515.4, ENSMUST00000096753.5
    Conserved Domains (4) summary
    smart00513
    Location:337
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    pfam13671
    Location:452597
    AAA_33; AAA domain
    cd12884
    Location:244415
    SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1
    cl17190
    Location:452634
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    8796765..8811507
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_003952813.2 RNA Sequence