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Glod5 glyoxalase domain containing 5 [ Mus musculus (house mouse) ]

Gene ID: 69824, updated on 25-Apr-2024

Summary

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Official Symbol
Glod5provided by MGI
Official Full Name
glyoxalase domain containing 5provided by MGI
Primary source
MGI:MGI:1917074
See related
Ensembl:ENSMUSG00000031163 AllianceGenome:MGI:1917074
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2010001H14Rik
Summary
Is expressed in lung and pituitary gland. Orthologous to human GLOD5 (glyoxalase domain containing 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in large intestine adult (RPKM 22.1), kidney adult (RPKM 8.7) and 3 other tissues See more
Orthologs
human all
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Genomic context

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See Glod5 in Genome Data Viewer
Location:
X A1.1; X 3.61 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (7870440..7884731, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (8004201..8018492, complement)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 39488 Neighboring gene proteasome (prosome, macropain) subunit, beta type 6, pseudogene Neighboring gene GATA binding protein 1 Neighboring gene predicted gene, 52419 Neighboring gene STARR-seq mESC enhancer starr_46683 Neighboring gene STARR-seq mESC enhancer starr_46684 Neighboring gene ribosomal protein L22, pseudogene 1 Neighboring gene oxidative stress-responsive serine-rich protein 1 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Phenotypic annotation of the mouse X chromosome. Cox BJ, et al. Genome Res, 2010 Aug. PMID 20548051, Free PMC Article
  2. Mutagenesis of diploid mammalian genes by gene entrapment. Lin Q, et al. Nucleic Acids Res, 2006. PMID 17062627, Free PMC Article
  3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Gene trapped (2) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
glyoxalase domain-containing protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027227.2 → NP_081503.1  glyoxalase domain-containing protein 5

    See identical proteins and their annotated locations for NP_081503.1

    Status: VALIDATED

    Source sequence(s)
    AK008008
    Consensus CDS
    CCDS29982.1
    UniProtKB/Swiss-Prot
    Q9D8I3
    Related
    ENSMUSP00000033503.3, ENSMUST00000033503.3
    Conserved Domains (1) summary
    cd07253
    Location:23 → 145
    Glo_EDI_BRP_like_2; This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    7870440..7884731 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006527699.4 → XP_006527762.1  glyoxalase domain-containing protein 5 isoform X1

    Conserved Domains (1) summary
    cd07253
    Location:1 → 115
    GLOD5; Human glyoxalase domain-containing protein 5 and similar proteins
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D8I3.1 GenPept UniProtKB/Swiss-Prot:Q9D8I3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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