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RXFP1 relaxin family peptide receptor 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 701107, updated on 17-Aug-2024

Summary

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Official Symbol
RXFP1provided by VGNC
Official Full Name
relaxin family peptide receptor 1provided by VGNC
Primary source
VGNC:VGNC:77056
See related
Ensembl:ENSMMUG00000004647
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
LGR7
Orthologs
human mouse all
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Genomic context

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See RXFP1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
19
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 5 NC_041758.1 (156135710..156260414)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 5 NC_027897.1 (158485159..158610102)

Chromosome 5 - NC_041758.1Genomic Context describing neighboring genes Neighboring gene U4 spliceosomal RNA Neighboring gene vasculin pseudogene Neighboring gene chromosome 5 C4orf46 homolog Neighboring gene electron transfer flavoprotein dehydrogenase Neighboring gene small nucleolar RNA U3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expression of LGR7 in the primate corpus luteum implicates the corpus luteum as a relaxin target organ. Maseelall PB, et al. Ann N Y Acad Sci, 2009 Apr. PMID 19416177, Free PMC Article
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
relaxin receptor 1
Names
leucine-rich repeat-containing G protein-coupled receptor 7
relaxin/insulin like family peptide receptor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041758.1 Reference Mmul_10 Primary Assembly

    Range
    156135710..156260414
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015139415.2 → XP_014994901.1  relaxin receptor 1 isoform X6

    UniProtKB/TrEMBL
    G7MS79
    Conserved Domains (4) summary
    cd00116
    Location:88 → 250
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:47 → 70
    LRR_RI; leucine-rich repeat [structural motif]
    pfam00001
    Location:343 → 600
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam13855
    Location:71 → 129
    LRR_8; Leucine rich repeat

  2. XM_001096574.4 → XP_001096574.1  relaxin receptor 1 isoform X1

    See identical proteins and their annotated locations for XP_001096574.1

    UniProtKB/TrEMBL
    I2CTQ4
    Related
    ENSMMUP00000006184.4, ENSMMUT00000006574.4
    Conserved Domains (5) summary
    cd00112
    Location:49 → 84
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00116
    Location:191 → 353
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:150 → 173
    LRR_RI; leucine-rich repeat [structural motif]
    pfam00001
    Location:446 → 703
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam13855
    Location:174 → 232
    LRR_8; Leucine rich repeat

  3. XM_015139411.2 → XP_014994897.1  relaxin receptor 1 isoform X2

    UniProtKB/TrEMBL
    I2CTQ4
    Conserved Domains (5) summary
    cd00112
    Location:49 → 84
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00116
    Location:191 → 353
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:150 → 173
    LRR_RI; leucine-rich repeat [structural motif]
    pfam00001
    Location:422 → 679
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam13855
    Location:174 → 232
    LRR_8; Leucine rich repeat

  4. XM_015139414.2 → XP_014994900.1  relaxin receptor 1 isoform X5

    UniProtKB/TrEMBL
    I2CTQ4
    Conserved Domains (5) summary
    cd00112
    Location:49 → 84
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    sd00033
    Location:150 → 173
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:174 → 232
    LRR_8; Leucine rich repeat
    cd14964
    Location:430 → 454
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:428 → 641
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  5. XM_015139413.2 → XP_014994899.1  relaxin receptor 1 isoform X4

    UniProtKB/TrEMBL
    I2CTQ4
    Conserved Domains (5) summary
    cd00112
    Location:49 → 84
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00116
    Location:191 → 353
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:150 → 173
    LRR_RI; leucine-rich repeat [structural motif]
    pfam00001
    Location:422 → 679
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam13855
    Location:174 → 232
    LRR_8; Leucine rich repeat

  6. XM_015139412.2 → XP_014994898.1  relaxin receptor 1 isoform X3

    UniProtKB/TrEMBL
    F6T6T5, I2CTQ4
    Related
    ENSMMUP00000006182.3, ENSMMUT00000006572.4
    Conserved Domains (5) summary
    cd00112
    Location:49 → 84
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00116
    Location:167 → 329
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:132 → 149
    LRR_RI; leucine-rich repeat [structural motif]
    pfam00001
    Location:422 → 679
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam13855
    Location:148 → 208
    LRR_8; Leucine rich repeat

RNA

  1. XR_003729834.1 RNA Sequence

  2. XR_003729833.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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