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OAS1 2'-5'-oligoadenylate synthetase 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 712265, updated on 17-Aug-2024

Summary

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Official Symbol
OAS1provided by VGNC
Official Full Name
2'-5'-oligoadenylate synthetase 1provided by VGNC
Primary source
VGNC:VGNC:75570
See related
Ensembl:ENSMMUG00000012782
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human all
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Genomic context

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See OAS1 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
7
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (112632314..112654759)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (112949175..112971674)

Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114671076 Neighboring gene rabphilin 3A Neighboring gene 2'-5'-oligoadenylate synthetase 3 Neighboring gene 2'-5'-oligoadenylate synthetase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 2'-5'-oligoadenylate synthetase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables double-stranded RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in defense response to virus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of viral genome replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of ribonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
2'-5'-oligoadenylate synthase 1
Names
2'-5' oligoadenylate stnthetase 1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
NP_001077418.1
XP_015008328.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001083949.1 → NP_001077418.1  2'-5'-oligoadenylate synthase 1

    See identical proteins and their annotated locations for NP_001077418.1

    Status: PROVISIONAL

    Source sequence(s)
    EF467666
    UniProtKB/TrEMBL
    A4LA99, A4LAA0
    Related
    ENSMMUP00000016793.4, ENSMMUT00000017932.4
    Conserved Domains (2) summary
    cd05400
    Location:29 → 166
    NT_2-5OAS_ClassI-CCAase; Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme
    pfam10421
    Location:163 → 343
    OAS1_C; 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041764.1 Reference Mmul_10 Primary Assembly

    Range
    112632314..112654759
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015152842.2 → XP_015008328.2  2'-5'-oligoadenylate synthase 1 isoform X1

    UniProtKB/TrEMBL
    A0A5F7ZSP7
    Related
    ENSMMUP00000068674.1, ENSMMUT00000081471.1
    Conserved Domains (2) summary
    cd05400
    Location:117 → 254
    NT_2-5OAS_ClassI-CCAase; Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme
    pfam10421
    Location:252 → 431
    OAS1_C; 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus
Nucleotide Protein
Heading Accession and Version

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