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HIPK2 homeodomain interacting protein kinase 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 716152, updated on 17-Aug-2024

Summary

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Official Symbol
HIPK2provided by VGNC
Official Full Name
homeodomain interacting protein kinase 2provided by VGNC
Primary source
VGNC:VGNC:73391
See related
Ensembl:ENSMMUG00000002481
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See HIPK2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
17
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (165976521..166196920, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (165914352..166103505, complement)

Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene hsc70-interacting protein pseudogene Neighboring gene enhancer of rudimentary homolog pseudogene Neighboring gene C-type lectin domain family 2 member L Neighboring gene uncharacterized LOC106997690 Neighboring gene uncharacterized LOC106997689 Neighboring gene uncharacterized LOC114677045 Neighboring gene uncharacterized LOC106997691 Neighboring gene thromboxane A synthase 1 Neighboring gene poly(ADP-ribose) polymerase family member 12

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Form deprivation modulates retinal neurogenesis in primate experimental myopia. Tkatchenko AV, et al. Proc Natl Acad Sci U S A, 2006 Mar 21. PMID 16537371, Free PMC Article
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables SMAD binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-threonine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in smoothened signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in PML body IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
homeodomain-interacting protein kinase 2
XP_028702200.1
XP_028702201.1
XP_028702202.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041756.1 Reference Mmul_10 Primary Assembly

    Range
    165976521..166196920 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028846367.1 → XP_028702200.1  homeodomain-interacting protein kinase 2 isoform X1

    UniProtKB/TrEMBL
    H9Z813
    Related
    ENSMMUP00000003338.3, ENSMMUT00000003530.3
    Conserved Domains (1) summary
    cd14227
    Location:183 → 537
    STKc_HIPK2; Catalytic domain of the Serine/Threonine Kinase, Homeodomain-Interacting Protein Kinase 2

  2. XM_028846369.1 → XP_028702202.1  homeodomain-interacting protein kinase 2 isoform X3

    UniProtKB/TrEMBL
    H9Z812
    Related
    ENSMMUP00000061338.1, ENSMMUT00000102703.1
    Conserved Domains (1) summary
    cd14227
    Location:183 → 537
    STKc_HIPK2; Catalytic domain of the Serine/Threonine Kinase, Homeodomain-Interacting Protein Kinase 2

  3. XM_028846368.1 → XP_028702201.1  homeodomain-interacting protein kinase 2 isoform X2

    UniProtKB/TrEMBL
    F7HGU8
    Conserved Domains (1) summary
    cd14227
    Location:176 → 530
    STKc_HIPK2; Catalytic domain of the Serine/Threonine Kinase, Homeodomain-Interacting Protein Kinase 2
Nucleotide Protein
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