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NCOA1 nuclear receptor coactivator 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 718524, updated on 17-Aug-2024

Summary

Official Symbol
NCOA1provided by VGNC
Official Full Name
nuclear receptor coactivator 1provided by VGNC
Primary source
VGNC:VGNC:75145
See related
Ensembl:ENSMMUG00000020838
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
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Genomic context

See NCOA1 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
20
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 13 NC_041766.1 (84216168..84333482, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 13 NC_027905.1 (24717877..24997836)

Chromosome 13 - NC_041766.1Genomic Context describing neighboring genes Neighboring gene adenylate cyclase 3 Neighboring gene centromere protein O Neighboring gene peptidyl-tRNA hydrolase domain containing 1 Neighboring gene U6 spliceosomal RNA Neighboring gene spidroin-1-like Neighboring gene 60S ribosomal protein L36a-like Neighboring gene intersectin 2

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables nuclear receptor binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables nuclear receptor coactivator activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cellular response to hormone stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
nuclear receptor coactivator 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041766.1 Reference Mmul_10 Primary Assembly

    Range
    84216168..84333482 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028831928.1XP_028687761.1  nuclear receptor coactivator 1 isoform X1

    UniProtKB/TrEMBL
    A0A5F8AMR3, H9G174
    Related
    ENSMMUP00000078250.1, ENSMMUT00000095493.1
    Conserved Domains (9) summary
    smart00353
    Location:3286
    HLH; helix loop helix domain
    cd00130
    Location:120213
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam07469
    Location:11501206
    DUF1518; Domain of unknown function (DUF1518)
    pfam08815
    Location:925971
    Nuc_rec_co-act; Nuclear receptor coactivator
    pfam08832
    Location:633709
    SRC-1; Steroid receptor coactivator
    pfam09606
    Location:9751309
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam14598
    Location:260370
    PAS_11; PAS domain
    pfam16279
    Location:742819
    DUF4927; Domain of unknown function (DUF4927)
    pfam16665
    Location:468591
    NCOA_u2; Unstructured region on nuclear receptor coactivator protein
  2. XM_028831930.1XP_028687763.1  nuclear receptor coactivator 1 isoform X3

    UniProtKB/TrEMBL
    A0A5K1VRH6, F7HQM5, H9G175
    Related
    ENSMMUP00000027425.4, ENSMMUT00000029312.4
    Conserved Domains (9) summary
    smart00353
    Location:3286
    HLH; helix loop helix domain
    cd00130
    Location:120213
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam07469
    Location:11501206
    DUF1518; Domain of unknown function (DUF1518)
    pfam08815
    Location:925971
    Nuc_rec_co-act; Nuclear receptor coactivator
    pfam08832
    Location:633709
    SRC-1; Steroid receptor coactivator
    pfam09606
    Location:9751309
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam14598
    Location:260370
    PAS_11; PAS domain
    pfam16279
    Location:742819
    DUF4927; Domain of unknown function (DUF4927)
    pfam16665
    Location:468591
    NCOA_u2; Unstructured region on nuclear receptor coactivator protein
  3. XM_028831929.1XP_028687762.1  nuclear receptor coactivator 1 isoform X2

    UniProtKB/TrEMBL
    H9ZER0
    Related
    ENSMMUP00000065983.1, ENSMMUT00000090323.1
    Conserved Domains (9) summary
    smart00353
    Location:3286
    HLH; helix loop helix domain
    cd00130
    Location:120213
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam07469
    Location:11501206
    DUF1518; Domain of unknown function (DUF1518)
    pfam08815
    Location:925971
    Nuc_rec_co-act; Nuclear receptor coactivator
    pfam08832
    Location:633709
    SRC-1; Steroid receptor coactivator
    pfam09606
    Location:9751309
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam14598
    Location:260370
    PAS_11; PAS domain
    pfam16279
    Location:742819
    DUF4927; Domain of unknown function (DUF4927)
    pfam16665
    Location:468591
    NCOA_u2; Unstructured region on nuclear receptor coactivator protein
  4. XM_028831931.1XP_028687764.1  nuclear receptor coactivator 1 isoform X3

    UniProtKB/TrEMBL
    A0A5K1VRH6, F7HQM5, H9G175
    Conserved Domains (9) summary
    smart00353
    Location:3286
    HLH; helix loop helix domain
    cd00130
    Location:120213
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam07469
    Location:11501206
    DUF1518; Domain of unknown function (DUF1518)
    pfam08815
    Location:925971
    Nuc_rec_co-act; Nuclear receptor coactivator
    pfam08832
    Location:633709
    SRC-1; Steroid receptor coactivator
    pfam09606
    Location:9751309
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam14598
    Location:260370
    PAS_11; PAS domain
    pfam16279
    Location:742819
    DUF4927; Domain of unknown function (DUF4927)
    pfam16665
    Location:468591
    NCOA_u2; Unstructured region on nuclear receptor coactivator protein