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NOTCH3 notch receptor 3 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 719119, updated on 5-Mar-2024

Summary

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Gene symbol
NOTCH3
Gene description
notch receptor 3
See related
Ensembl:ENSMMUG00000013637
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See NOTCH3 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
33
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (14761814..14803537, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (15061120..15102789, complement)

Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 1 subfamily I member 1 Neighboring gene synapse defective Rho GTPase homolog 1 Neighboring gene ilvB acetolactate synthase like Neighboring gene epoxide hydrolase 3 Neighboring gene bromodomain containing 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of developmental process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neurogenic locus notch homolog protein 3
Names
neurogenic locus notch homolog protein 3-like
notch 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041772.1 Reference Mmul_10 Primary Assembly

    Range
    14761814..14803537 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015123166.2 → XP_014978652.2  neurogenic locus notch homolog protein 3

    UniProtKB/TrEMBL
    F7GL52, H9Z9C9
    Related
    ENSMMUP00000017928.4, ENSMMUT00000019144.4
    Conserved Domains (11) summary
    smart00004
    Location:1421 → 1458
    NL; Domain found in Notch and Lin-12
    smart00179
    Location:657 → 686
    EGF_CA; Calcium-binding EGF-like domain
    PHA03095
    Location:1779 → 1992
    PHA03095; ankyrin-like protein; Provisional
    PHA03247
    Location:2027 → 2317
    PHA03247; large tegument protein UL36; Provisional
    cd00054
    Location:158 → 195
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    sd00045
    Location:1905 → 1936
    ANK; ANK repeat [structural motif]
    pfam06816
    Location:1508 → 1557
    NOD; NOTCH protein
    pfam07684
    Location:1578 → 1637
    NODP; NOTCH protein
    pfam11936
    Location:2212 → 2273
    DUF3454; Domain of unknown function (DUF3454)
    pfam00066
    Location:1385 → 1418
    Notch; LNR domain
    pfam12796
    Location:1910 → 2002
    Ank_2; Ankyrin repeats (3 copies)
Nucleotide Protein
Heading Accession and Version

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