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Shisal1 shisa like 1 [ Mus musculus (house mouse) ]

Gene ID: 72301, updated on 17-Aug-2024

Summary

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Official Symbol
Shisal1provided by MGI
Official Full Name
shisa like 1provided by MGI
Primary source
MGI:MGI:1919551
See related
Ensembl:ENSMUSG00000062760 AllianceGenome:MGI:1919551
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Kiaa1644; 1810041L15Rik
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including central nervous system; dorsal root ganglion; olfactory epithelium; and retina. Orthologous to human SHISAL1 (shisa like 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in bladder adult (RPKM 26.9), frontal lobe adult (RPKM 8.1) and 14 other tissues See more
Orthologs
human all
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Genomic context

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Location:
15 E2; 15 39.78 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (84263404..84367061, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (84379203..84482860, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene parvin, gamma Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:84185775-84185884 Neighboring gene N(alpha)-acetyltransferase 10, NatA catalytic subunitNalpha acetyltransferase 10 pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:84214597-84214798 Neighboring gene STARR-seq mESC enhancer starr_39362 Neighboring gene predicted gene, 46527 Neighboring gene STARR-seq mESC enhancer starr_39363 Neighboring gene predicted gene, 33830 Neighboring gene STARR-seq mESC enhancer starr_39364 Neighboring gene STARR-seq mESC enhancer starr_39365 Neighboring gene predicted gene, 33966 Neighboring gene STARR-seq mESC enhancer starr_39367 Neighboring gene predicted gene, 34027

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Discrete gene sets depend on POU domain transcription factor Brn3b/Brn-3.2/POU4f2 for their expression in the mouse embryonic retina. Mu X, et al. Development, 2004 Mar. PMID 14973295
  2. Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2003 Aug 31. PMID 14621295
  3. Genomic analysis of mouse retinal development. Blackshaw S, et al. PLoS Biol, 2004 Sep. PMID 15226823, Free PMC Article
  4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Clone Names

  • 1810041L15Rik

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein shisa-like-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163145.2 → NP_001156617.2  protein shisa-like-1 isoform 1 precursor

    Status: VALIDATED

    Description
    Transcript Variant: Variants 1, 3, 4 and 5 encode the same isoform (1).
    Source sequence(s)
    AI415268, AK162836, BC062953
    Consensus CDS
    CCDS49687.1
    UniProtKB/Swiss-Prot
    Q0VBP7, Q6P5D2, Q6ZPK6
    Related
    ENSMUSP00000079575.4, ENSMUST00000080751.10
    Conserved Domains (1) summary
    pfam13908
    Location:30 → 70
    Shisa; Wnt and FGF inhibitory regulator

  2. NM_001347543.2 → NP_001334472.1  protein shisa-like-1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL603714
    Consensus CDS
    CCDS84184.1
    UniProtKB/TrEMBL
    A0A087WSN1
    Related
    ENSMUSP00000141117.2, ENSMUST00000189248.7
    Conserved Domains (1) summary
    pfam13908
    Location:51 → 91
    Shisa; Wnt and FGF inhibitory regulator

  3. NM_001374162.1 → NP_001361091.1  protein shisa-like-1 isoform 1 precursor

    Status: VALIDATED

    Description
    Transcript Variant: Variants 1, 3, 4 and 5 encode the same isoform (1).
    Source sequence(s)
    AL603714
    UniProtKB/Swiss-Prot
    Q0VBP7, Q6P5D2, Q6ZPK6
    Conserved Domains (1) summary
    pfam13908
    Location:30 → 70
    Shisa; Wnt and FGF inhibitory regulator

  4. NM_001374163.1 → NP_001361092.1  protein shisa-like-1 isoform 1 precursor

    Status: VALIDATED

    Description
    Transcript Variant: Variants 1, 3, 4 and 5 encode the same isoform (1).
    Source sequence(s)
    AL603714
    UniProtKB/Swiss-Prot
    Q0VBP7, Q6P5D2, Q6ZPK6
    Conserved Domains (1) summary
    pfam13908
    Location:30 → 70
    Shisa; Wnt and FGF inhibitory regulator

  5. NM_001374164.1 → NP_001361093.1  protein shisa-like-1 isoform 1 precursor

    Status: VALIDATED

    Description
    Transcript Variant: Variants 1, 3, 4 and 5 encode the same isoform (1).
    Source sequence(s)
    AL603714
    UniProtKB/Swiss-Prot
    Q0VBP7, Q6P5D2, Q6ZPK6
    Conserved Domains (1) summary
    pfam13908
    Location:30 → 70
    Shisa; Wnt and FGF inhibitory regulator

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    84263404..84367061 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006521445.4 → XP_006521508.1  protein shisa-like-1 isoform X1

    See identical proteins and their annotated locations for XP_006521508.1

    UniProtKB/TrEMBL
    H7BX53
    Conserved Domains (1) summary
    pfam13908
    Location:31 → 71
    Shisa; Wnt and FGF inhibitory regulator

  2. XM_006521443.5 → XP_006521506.1  protein shisa-like-1 isoform X1

    See identical proteins and their annotated locations for XP_006521506.1

    UniProtKB/TrEMBL
    H7BX53
    Conserved Domains (1) summary
    pfam13908
    Location:31 → 71
    Shisa; Wnt and FGF inhibitory regulator
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q0VBP7.1 GenPept UniProtKB/Swiss-Prot:Q0VBP7

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