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nxf1a nuclear RNA export factor 1a [ Danio rerio (zebrafish) ]

Gene ID: 751719, updated on 14-Nov-2024

Summary

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Official Symbol
nxf1aprovided by ZNC
Official Full Name
nuclear RNA export factor 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060825-299
See related
Ensembl:ENSDARG00000086017 AllianceGenome:ZFIN:ZDB-GENE-060825-299
Gene type
protein coding
RefSeq status
PREDICTED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:153681
Summary
Predicted to enable RNA binding activity. Predicted to be involved in poly(A)+ mRNA export from nucleus. Predicted to act upstream of or within mRNA export from nucleus. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Orthologous to human NXF1 (nuclear RNA export factor 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See nxf1a in Genome Data Viewer
Location:
chromosome: 14
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (8893487..8940478, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (8587471..8634464, complement)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene tRNA methyltransferase activator subunit 11-2 Neighboring gene autophagy related 2A Neighboring gene uncharacterized LOC137487565 Neighboring gene ribosomal protein S6 kinase a, like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Processing of fish Ig heavy chain transcripts: diverse splicing patterns and unusual nonsense mediated decay. Quiniou SM, et al. Dev Comp Immunol, 2011 Sep. PMID 21168434
  2. Transcriptomic analyses reveal novel genes with sexually dimorphic expression in the zebrafish gonad and brain. Sreenivasan R, et al. PLoS One, 2008 Mar 12. PMID 18335061, Free PMC Article
  3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC153681

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within mRNA export from nucleus IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within mRNA transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC751719

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001045429.1 → NP_001038894.1  uncharacterized protein LOC751719

    See identical proteins and their annotated locations for NP_001038894.1

    Status: PREDICTED

    Source sequence(s)
    BC122378
    UniProtKB/TrEMBL
    Q0P3Y8
    Related
    ENSDARP00000109457.1, ENSDART00000129030.3
    Conserved Domains (5) summary
    cd00780
    Location:413 → 561
    NTF2; Nuclear transport factor 2 (NTF2) domain plays an important role in the trafficking of macromolecules, ions and small molecules between the cytoplasm and nucleus. This bi-directional transport of macromolecules across the nuclear envelope requires many ...
    sd00035
    Location:249 → 291
    LRR_NTF; leucine-rich repeat [structural motif]
    pfam09162
    Location:142 → 223
    Tap-RNA_bind; Tap, RNA-binding
    pfam12799
    Location:290 → 336
    LRR_4; Leucine Rich repeats (2 copies)
    cl21463
    Location:579 → 610
    UBA_like_SF; UBA domain-like superfamily

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    8893487..8940478 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009307743.4 → XP_009306018.1  uncharacterized protein LOC751719 isoform X1

    UniProtKB/TrEMBL
    A0A8M3AZK2
    Conserved Domains (5) summary
    smart00804
    Location:579 → 641
    TAP_C; C-terminal domain of vertebrate Tap protein
    cd00780
    Location:413 → 561
    NTF2; Nuclear transport factor 2 (NTF2) domain plays an important role in the trafficking of macromolecules, ions and small molecules between the cytoplasm and nucleus. This bi-directional transport of macromolecules across the nuclear envelope requires many ...
    sd00035
    Location:249 → 291
    LRR_NTF; leucine-rich repeat [structural motif]
    pfam09162
    Location:142 → 223
    Tap-RNA_bind; Tap, RNA-binding
    pfam12799
    Location:290 → 336
    LRR_4; Leucine Rich repeats (2 copies)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394892.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    254788..259076 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394893.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    1..30981 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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