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nucb1 nucleobindin 1 [ Danio rerio (zebrafish) ]

Gene ID: 751753, updated on 14-Nov-2024

Summary

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Official Symbol
nucb1provided by ZNC
Official Full Name
nucleobindin 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-060825-222
See related
Ensembl:ENSDARG00000054833 AllianceGenome:ZFIN:ZDB-GENE-060825-222
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:153192
Summary
Predicted to enable calcium ion binding activity. Predicted to be located in Golgi apparatus; extracellular region; and membrane. Predicted to be active in endoplasmic reticulum-Golgi intermediate compartment. Orthologous to human NUCB1 (nucleobindin 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See nucb1 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (30140303..30153236, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (30009749..30022416, complement)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene neurotrophin-3 Neighboring gene PTPRF interacting protein alpha 3 Neighboring gene cyclin Dx Neighboring gene TBC1 domain family, member 17

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Nesfatin-1-like peptide is a negative regulator of cardiovascular functions in zebrafish and goldfish. Sundarrajan L, et al. Gen Comp Endocrinol, 2021 Nov 1. PMID 34453930
  2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC153192

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
nucleobindin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001045463.1 → NP_001038928.1  nucleobindin-1 precursor

    See identical proteins and their annotated locations for NP_001038928.1

    Status: PROVISIONAL

    Source sequence(s)
    BC122181
    UniProtKB/TrEMBL
    Q0P4B3
    Related
    ENSDARP00000071557.5, ENSDART00000077089.7
    Conserved Domains (1) summary
    pfam13499
    Location:239 → 312
    EF-hand_7; EF-hand domain pair

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    30140303..30153236 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005163951.5 → XP_005164008.1  nucleobindin-1 isoform X1

    UniProtKB/TrEMBL
    A0A8M2BBG2
    Conserved Domains (1) summary
    pfam13499
    Location:239 → 312
    EF-hand_7; EF-hand domain pair
Nucleotide Protein
Heading Accession and Version

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