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ero1b endoplasmic reticulum oxidoreductase 1 beta [ Danio rerio (zebrafish) ]

Gene ID: 767700, updated on 12-Sep-2024

Summary

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Official Symbol
ero1bprovided by ZNC
Official Full Name
endoplasmic reticulum oxidoreductase 1 betaprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060929-744
See related
Ensembl:ENSDARG00000103915 AllianceGenome:ZFIN:ZDB-GENE-060929-744
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
ero1lb; zgc:153032
Summary
Predicted to enable protein-disulfide reductase activity. Predicted to be involved in protein folding in endoplasmic reticulum. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human ERO1B (endoplasmic reticulum oxidoreductase 1 beta). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See ero1b in Genome Data Viewer
Location:
chromosome: 11
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (44502402..44522586)
105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (44240457..44260450)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene mitofusin 1b Neighboring gene si:ch1073-365p7.2 Neighboring gene G protein-coupled receptor 137Bb Neighboring gene nidogen 1b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. High-content screen using zebrafish (Danio rerio) embryos identifies a novel kinase activator and inhibitor. Geldenhuys WJ, et al. Bioorg Med Chem Lett, 2017 May 1. PMID 28320616, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC153032

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables FAD binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein-disulfide reductase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein-disulfide reductase activity IEA
Inferred from Electronic Annotation
more info
  
enables thiol oxidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein folding in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within protein folding in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ERO1-like protein beta
Names
ERO1-like beta
endoplasmic reticulum oxidoreductase beta

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001076638.1 → NP_001070106.1  ERO1-like protein beta precursor

    Status: PROVISIONAL

    Source sequence(s)
    BC124220
    UniProtKB/TrEMBL
    Q08CJ0
    Related
    ENSDARP00000139494.1, ENSDART00000169295.3
    Conserved Domains (1) summary
    pfam04137
    Location:48 → 446
    ERO1; Endoplasmic Reticulum Oxidoreductin 1 (ERO1)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    44502402..44522586
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005172944.5 → XP_005173001.1  ERO1-like protein beta isoform X1

    UniProtKB/TrEMBL
    A0A8M2BK75
    Conserved Domains (1) summary
    pfam04137
    Location:77 → 475
    ERO1; Endoplasmic Reticulum Oxidoreductin 1 (ERO1)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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