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cep44 centrosomal protein 44 [ Danio rerio (zebrafish) ]

Gene ID: 767769, updated on 2-Nov-2024

Summary

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Official Symbol
cep44provided by ZNC
Official Full Name
centrosomal protein 44provided by ZNC
Primary source
ZFIN:ZDB-GENE-060929-392
See related
Ensembl:ENSDARG00000053106 AllianceGenome:ZFIN:ZDB-GENE-060929-392
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:153894
Summary
Predicted to be involved in centriole replication and centriole-centriole cohesion. Predicted to be located in centriole; cytoplasm; and midbody. Predicted to be active in centrosome and spindle pole. Is expressed in head and post-vent region. Orthologous to human CEP44 (centrosomal protein 44). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See cep44 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (38338983..38374799)
105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (37643170..37655621)

Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene heart and neural crest derivatives expressed 2 Neighboring gene uncharacterized LOC137495612 Neighboring gene F-box protein 8 Neighboring gene 15-hydroxyprostaglandin dehydrogenase Neighboring gene glycine receptor, alpha 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Individual knock out of glycine receptor alpha subunits identifies a specific requirement of glra1 for motor function in zebrafish. Samarut E, et al. PLoS One, 2019. PMID 31048868, Free PMC Article
  2. Prpf31 is essential for the survival and differentiation of retinal progenitor cells by modulating alternative splicing. Li J, et al. Nucleic Acids Res, 2021 Feb 26. PMID 33476374, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC153894

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in centriole replication IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in centriole-centriole cohesion IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in centriole IEA
Inferred from Electronic Annotation
more info
  
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in midbody IEA
Inferred from Electronic Annotation
more info
  
is_active_in spindle pole IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
centrosomal protein of 44 kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001076736.2 → NP_001070204.2  centrosomal protein of 44 kDa

    Status: VALIDATED

    Source sequence(s)
    CU928070
    UniProtKB/TrEMBL
    A0A8M1NBH8, F6NJX7
    Related
    ENSDARP00000069571.4, ENSDART00000075086.5
    Conserved Domains (1) summary
    pfam15007
    Location:5 → 129
    CEP44; Centrosomal spindle body, CEP44

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007112.7 Reference GRCz11 Primary Assembly

    Range
    38338983..38374799
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068220854.1 → XP_068076955.1  centrosomal protein of 44 kDa isoform X1

  2. XM_068220855.1 → XP_068076956.1  centrosomal protein of 44 kDa isoform X2

  3. XM_068220857.1 → XP_068076958.1  centrosomal protein of 44 kDa isoform X4

  4. XM_068220856.1 → XP_068076957.1  centrosomal protein of 44 kDa isoform X3

  5. XM_021475843.2 → XP_021331518.1  centrosomal protein of 44 kDa isoform X5

    UniProtKB/TrEMBL
    A0A8M9PWN9
    Conserved Domains (1) summary
    pfam15007
    Location:5 → 129
    CEP44; Centrosomal spindle body, CEP44
Nucleotide Protein Strain
Heading Accession and Version

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