U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

tusc2a tumor suppressor 2, mitochondrial calcium regulator a [ Danio rerio (zebrafish) ]

Gene ID: 768156, updated on 2-Nov-2024

Summary

Official Symbol
tusc2aprovided by ZNC
Official Full Name
tumor suppressor 2, mitochondrial calcium regulator aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-061013-612
See related
Ensembl:ENSDARG00000099817 AllianceGenome:ZFIN:ZDB-GENE-061013-612
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:153746
Summary
Predicted to be involved in inflammatory response and regulation of mitochondrial membrane potential. Predicted to be active in mitochondrion. Orthologous to human TUSC2 (tumor suppressor 2, mitochondrial calcium regulator). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See tusc2a in Genome Data Viewer
Location:
chromosome: 6
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (54117004..54126423, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (54108896..54118298, complement)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene fragile histidine triad diadenosine triphosphatase Neighboring gene hyaluronidase 2a Neighboring gene high mobility group AT-hook 1b Neighboring gene nudix (nucleoside diphosphate linked moiety X)-type motif 3b

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in inflammatory response IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of mitochondrial membrane potential IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
tumor suppressor 2, mitochondrial calcium regulator a
Names
tumor suppressor candidate 2a

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001077299.2NP_001070767.2  tumor suppressor 2, mitochondrial calcium regulator a

    Status: VALIDATED

    Source sequence(s)
    CU694224, CU856136
    Related
    ENSDARP00000138164.1, ENSDART00000161059.2

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    54117004..54126423 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068221796.1XP_068077897.1  tumor suppressor 2, mitochondrial calcium regulator a isoform X1