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ZNF133 zinc finger protein 133 [ Homo sapiens (human) ]

Gene ID: 7692, updated on 17-Jun-2024

Summary

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Official Symbol
ZNF133provided by HGNC
Official Full Name
zinc finger protein 133provided by HGNC
Primary source
HGNC:HGNC:12917
See related
Ensembl:ENSG00000125846 MIM:604075; AllianceGenome:HGNC:12917
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF150; pHZ-13; pHZ-66
Summary
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in skin (RPKM 1.6), ovary (RPKM 1.5) and 25 other tissues See more
Orthologs
all
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Genomic context

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See ZNF133 in Genome Data Viewer
Location:
20p11.23
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (18288527..18316996)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (18339617..18368084)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (18269171..18297640)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124904876 Neighboring gene uncharacterized LOC105372551 Neighboring gene RNA, U2 small nuclear 56, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17581 Neighboring gene H3K27ac hESC enhancer GRCh37_chr20:18268873-18269778 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17583 Neighboring gene RN7SK pseudogene 74 Neighboring gene ZNF133 antisense RNA 1 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr20:18304193-18304816 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr20:18309992-18311191 Neighboring gene RNY4 pseudogene 11 Neighboring gene small nucleolar RNA U13

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. ZNF133 is associated with infliximab responsiveness in patients with inflammatory bowel diseases. Jung ES, et al. J Gastroenterol Hepatol, 2019 Oct. PMID 30851117
  2. Human alcoholism studies of genes identified through mouse quantitative trait locus analysis. Ehringer MA, et al. Addict Biol, 2002 Oct. PMID 14578011
  3. ZNF133 is a potent suppressor in breast carcinogenesis through dampening L1CAM, a driver for tumor progression. Li L, et al. Oncogene, 2023 Jun. PMID 37221223
  4. PIAS1 interacts with the KRAB zinc finger protein, ZNF133, via zinc finger motifs and regulates its transcriptional activity. Lee SJ, et al. Exp Mol Med, 2007 Aug 31. PMID 17934332
  5. Silencing of RNA polymerases II and III-dependent transcription by the KRAB protein domain of KOX1, a Krüppel-type zinc finger factor. Moosmann P, et al. Biol Chem, 1997 Jul. PMID 9278146

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ZNF133 is a potent suppressor in breast carcinogenesis through dampening L1CAM, a driver for tumor progression.
    Title: ZNF133 is a potent suppressor in breast carcinogenesis through dampening L1CAM, a driver for tumor progression.
  2. ZNF133 SNPs are associated with infliximab responsiveness in patients crohn's disease and ulcerative colitis.
    Title: ZNF133 is associated with infliximab responsiveness in patients with inflammatory bowel diseases.
  3. the transcriptional repressor activity of ZNF133 is regulated by both the KRAB domain and the zinc finger motifs, and that the repressive effect by zinc finger motifs is mediated by PIAS1
    Title: PIAS1 interacts with the KRAB zinc finger protein, ZNF133, via zinc finger motifs and regulates its transcriptional activity.
  4. response to alcohol may be expressed by one of these candidate genes, zinc finger 133 (Znf133
    Title: Human alcoholism studies of genes identified through mouse quantitative trait locus analysis.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity TAS
Traceable Author Statement
more info
 PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 133
Names
zinc finger protein 133 (clone pHZ-13)
zinc finger protein 150 (pHZ-66)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001083330.4 → NP_001076799.2  zinc finger protein 133 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS13134.1
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:214 → 623
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:271 → 291
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. NM_001282995.3 → NP_001269924.2  zinc finger protein 133 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS13134.1
    Related
    ENSP00000400897.3, ENST00000396026.7
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:214 → 623
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:271 → 291
    ZF_C2H2; C2H2 Zn finger [structural motif]

  3. NM_001282996.3 → NP_001269925.2  zinc finger protein 133 isoform b

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Conserved Domains (3) summary
    smart00349
    Location:4 → 63
    KRAB; krueppel associated box
    COG5048
    Location:232 → 641
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:289 → 309
    ZF_C2H2; C2H2 Zn finger [structural motif]

  4. NM_001282997.3 → NP_001269926.2  zinc finger protein 133 isoform c

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS63234.1
    UniProtKB/Swiss-Prot
    A8K5S4, B4DHU7, B4DIB8, B7ZAS1, F5H289, J3KQ11, J3KQJ0, P52736, Q53XU1, Q5JXV8, Q9BUV2, Q9H443
    Related
    ENSP00000383945.1, ENST00000401790.6
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:215 → 624
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272 → 292
    ZF_C2H2; C2H2 Zn finger [structural motif]

  5. NM_001282998.3 → NP_001269927.2  zinc finger protein 133 isoform c

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS63234.1
    UniProtKB/Swiss-Prot
    A8K5S4, B4DHU7, B4DIB8, B7ZAS1, F5H289, J3KQ11, J3KQJ0, P52736, Q53XU1, Q5JXV8, Q9BUV2, Q9H443
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:215 → 624
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272 → 292
    ZF_C2H2; C2H2 Zn finger [structural motif]

  6. NM_001282999.3 → NP_001269928.2  zinc finger protein 133 isoform c

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS63234.1
    UniProtKB/Swiss-Prot
    A8K5S4, B4DHU7, B4DIB8, B7ZAS1, F5H289, J3KQ11, J3KQJ0, P52736, Q53XU1, Q5JXV8, Q9BUV2, Q9H443
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:215 → 624
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272 → 292
    ZF_C2H2; C2H2 Zn finger [structural motif]

  7. NM_001283000.3 → NP_001269929.2  zinc finger protein 133 isoform c

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS63234.1
    UniProtKB/Swiss-Prot
    A8K5S4, B4DHU7, B4DIB8, B7ZAS1, F5H289, J3KQ11, J3KQJ0, P52736, Q53XU1, Q5JXV8, Q9BUV2, Q9H443
    Related
    ENSP00000481326.1, ENST00000622607.4
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:215 → 624
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272 → 292
    ZF_C2H2; C2H2 Zn finger [structural motif]

  8. NM_001283001.3 → NP_001269930.2  zinc finger protein 133 isoform c

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS63234.1
    UniProtKB/Swiss-Prot
    A8K5S4, B4DHU7, B4DIB8, B7ZAS1, F5H289, J3KQ11, J3KQJ0, P52736, Q53XU1, Q5JXV8, Q9BUV2, Q9H443
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:215 → 624
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272 → 292
    ZF_C2H2; C2H2 Zn finger [structural motif]

  9. NM_001283002.3 → NP_001269931.2  zinc finger protein 133 isoform d

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS63233.1
    Related
    ENSP00000487315.1, ENST00000628216.2
    Conserved Domains (3) summary
    smart00349
    Location:4 → 63
    KRAB; krueppel associated box
    COG5048
    Location:218 → 627
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:275 → 295
    ZF_C2H2; C2H2 Zn finger [structural motif]

  10. NM_001283003.3 → NP_001269932.2  zinc finger protein 133 isoform e

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Conserved Domains (2) summary
    COG5048
    Location:152 → 561
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:209 → 229
    ZF_C2H2; C2H2 Zn finger [structural motif]

  11. NM_001283004.3 → NP_001269933.2  zinc finger protein 133 isoform e

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Conserved Domains (2) summary
    COG5048
    Location:152 → 561
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:209 → 229
    ZF_C2H2; C2H2 Zn finger [structural motif]

  12. NM_001283005.3 → NP_001269934.2  zinc finger protein 133 isoform i

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS74703.2
    Related
    ENSP00000485741.1, ENST00000630056.1
    Conserved Domains (2) summary
    COG5048
    Location:120 → 529
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:177 → 197
    ZF_C2H2; C2H2 Zn finger [structural motif]

  13. NM_001283006.3 → NP_001269935.2  zinc finger protein 133 isoform i

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS74703.2
    Conserved Domains (2) summary
    COG5048
    Location:120 → 529
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:177 → 197
    ZF_C2H2; C2H2 Zn finger [structural motif]

  14. NM_001283007.3 → NP_001269936.2  zinc finger protein 133 isoform i

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS74703.2
    Related
    ENSP00000439427.3, ENST00000535822.6
    Conserved Domains (2) summary
    COG5048
    Location:120 → 529
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:177 → 197
    ZF_C2H2; C2H2 Zn finger [structural motif]

  15. NM_001283008.3 → NP_001269937.2  zinc finger protein 133 isoform i

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS74703.2
    Conserved Domains (2) summary
    COG5048
    Location:120 → 529
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:177 → 197
    ZF_C2H2; C2H2 Zn finger [structural motif]

  16. NM_001352450.2 → NP_001339379.2  zinc finger protein 133 isoform e

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Conserved Domains (2) summary
    COG5048
    Location:152 → 561
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:209 → 229
    ZF_C2H2; C2H2 Zn finger [structural motif]

  17. NM_001352451.2 → NP_001339380.2  zinc finger protein 133 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS13134.1
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:214 → 623
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:271 → 291
    ZF_C2H2; C2H2 Zn finger [structural motif]

  18. NM_001352452.2 → NP_001339381.2  zinc finger protein 133 isoform c

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS63234.1
    UniProtKB/Swiss-Prot
    A8K5S4, B4DHU7, B4DIB8, B7ZAS1, F5H289, J3KQ11, J3KQJ0, P52736, Q53XU1, Q5JXV8, Q9BUV2, Q9H443
    Related
    ENSP00000406638.2, ENST00000425686.3
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:215 → 624
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272 → 292
    ZF_C2H2; C2H2 Zn finger [structural motif]

  19. NM_001352453.2 → NP_001339382.2  zinc finger protein 133 isoform i

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS74703.2
    Conserved Domains (2) summary
    COG5048
    Location:120 → 529
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:177 → 197
    ZF_C2H2; C2H2 Zn finger [structural motif]

  20. NM_001352454.2 → NP_001339383.2  zinc finger protein 133 isoform c

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS63234.1
    UniProtKB/Swiss-Prot
    A8K5S4, B4DHU7, B4DIB8, B7ZAS1, F5H289, J3KQ11, J3KQJ0, P52736, Q53XU1, Q5JXV8, Q9BUV2, Q9H443
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:215 → 624
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272 → 292
    ZF_C2H2; C2H2 Zn finger [structural motif]

  21. NM_001352455.2 → NP_001339384.2  zinc finger protein 133 isoform c

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS63234.1
    UniProtKB/Swiss-Prot
    A8K5S4, B4DHU7, B4DIB8, B7ZAS1, F5H289, J3KQ11, J3KQJ0, P52736, Q53XU1, Q5JXV8, Q9BUV2, Q9H443
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:215 → 624
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272 → 292
    ZF_C2H2; C2H2 Zn finger [structural motif]

  22. NM_001352456.2 → NP_001339385.2  zinc finger protein 133 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS13134.1
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:214 → 623
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:271 → 291
    ZF_C2H2; C2H2 Zn finger [structural motif]

  23. NM_001352457.2 → NP_001339386.2  zinc finger protein 133 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS13134.1
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:214 → 623
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:271 → 291
    ZF_C2H2; C2H2 Zn finger [structural motif]

  24. NM_001352458.2 → NP_001339387.2  zinc finger protein 133 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS13134.1
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:214 → 623
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:271 → 291
    ZF_C2H2; C2H2 Zn finger [structural motif]

  25. NM_001352459.2 → NP_001339388.2  zinc finger protein 133 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS13134.1
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:214 → 623
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:271 → 291
    ZF_C2H2; C2H2 Zn finger [structural motif]

  26. NM_001352460.2 → NP_001339389.2  zinc finger protein 133 isoform e

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Conserved Domains (2) summary
    COG5048
    Location:152 → 561
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:209 → 229
    ZF_C2H2; C2H2 Zn finger [structural motif]

  27. NM_001352461.2 → NP_001339390.2  zinc finger protein 133 isoform e

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Conserved Domains (2) summary
    COG5048
    Location:152 → 561
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:209 → 229
    ZF_C2H2; C2H2 Zn finger [structural motif]

  28. NM_001352462.2 → NP_001339391.2  zinc finger protein 133 isoform k

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Conserved Domains (2) summary
    COG5048
    Location:151 → 560
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:208 → 228
    ZF_C2H2; C2H2 Zn finger [structural motif]

  29. NM_001352463.2 → NP_001339392.2  zinc finger protein 133 isoform c

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS63234.1
    UniProtKB/Swiss-Prot
    A8K5S4, B4DHU7, B4DIB8, B7ZAS1, F5H289, J3KQ11, J3KQJ0, P52736, Q53XU1, Q5JXV8, Q9BUV2, Q9H443
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:215 → 624
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272 → 292
    ZF_C2H2; C2H2 Zn finger [structural motif]

  30. NM_001352464.2 → NP_001339393.2  zinc finger protein 133 isoform c

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS63234.1
    UniProtKB/Swiss-Prot
    A8K5S4, B4DHU7, B4DIB8, B7ZAS1, F5H289, J3KQ11, J3KQJ0, P52736, Q53XU1, Q5JXV8, Q9BUV2, Q9H443
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:215 → 624
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272 → 292
    ZF_C2H2; C2H2 Zn finger [structural motif]

  31. NM_001387295.1 → NP_001374224.1  zinc finger protein 133 isoform l

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:252 → 661
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:309 → 329
    ZF_C2H2; C2H2 Zn finger [structural motif]

  32. NM_001387296.1 → NP_001374225.1  zinc finger protein 133 isoform m

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:251 → 660
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:308 → 328
    ZF_C2H2; C2H2 Zn finger [structural motif]

  33. NM_001387297.1 → NP_001374226.1  zinc finger protein 133 isoform n

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Conserved Domains (3) summary
    smart00349
    Location:4 → 63
    KRAB; krueppel associated box
    COG5048
    Location:217 → 626
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:274 → 294
    ZF_C2H2; C2H2 Zn finger [structural motif]

  34. NM_001387298.1 → NP_001374227.1  zinc finger protein 133 isoform c

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS63234.1
    UniProtKB/Swiss-Prot
    A8K5S4, B4DHU7, B4DIB8, B7ZAS1, F5H289, J3KQ11, J3KQJ0, P52736, Q53XU1, Q5JXV8, Q9BUV2, Q9H443
    Related
    ENSP00000346090.3, ENST00000316358.8
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:215 → 624
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272 → 292
    ZF_C2H2; C2H2 Zn finger [structural motif]

  35. NM_001387299.1 → NP_001374228.1  zinc finger protein 133 isoform c

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS63234.1
    UniProtKB/Swiss-Prot
    A8K5S4, B4DHU7, B4DIB8, B7ZAS1, F5H289, J3KQ11, J3KQJ0, P52736, Q53XU1, Q5JXV8, Q9BUV2, Q9H443
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:215 → 624
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272 → 292
    ZF_C2H2; C2H2 Zn finger [structural motif]

  36. NM_001387300.1 → NP_001374229.1  zinc finger protein 133 isoform c

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS63234.1
    UniProtKB/Swiss-Prot
    A8K5S4, B4DHU7, B4DIB8, B7ZAS1, F5H289, J3KQ11, J3KQJ0, P52736, Q53XU1, Q5JXV8, Q9BUV2, Q9H443
    Related
    ENSP00000513883.1, ENST00000698704.1
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:215 → 624
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272 → 292
    ZF_C2H2; C2H2 Zn finger [structural motif]

  37. NM_001387301.1 → NP_001374230.1  zinc finger protein 133 isoform c

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS63234.1
    UniProtKB/Swiss-Prot
    A8K5S4, B4DHU7, B4DIB8, B7ZAS1, F5H289, J3KQ11, J3KQJ0, P52736, Q53XU1, Q5JXV8, Q9BUV2, Q9H443
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:215 → 624
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272 → 292
    ZF_C2H2; C2H2 Zn finger [structural motif]

  38. NM_001387302.1 → NP_001374231.1  zinc finger protein 133 isoform c

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS63234.1
    UniProtKB/Swiss-Prot
    A8K5S4, B4DHU7, B4DIB8, B7ZAS1, F5H289, J3KQ11, J3KQJ0, P52736, Q53XU1, Q5JXV8, Q9BUV2, Q9H443
    Related
    ENSP00000513884.1, ENST00000698705.1
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:215 → 624
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272 → 292
    ZF_C2H2; C2H2 Zn finger [structural motif]

  39. NM_001387303.1 → NP_001374232.1  zinc finger protein 133 isoform c

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS63234.1
    UniProtKB/Swiss-Prot
    A8K5S4, B4DHU7, B4DIB8, B7ZAS1, F5H289, J3KQ11, J3KQJ0, P52736, Q53XU1, Q5JXV8, Q9BUV2, Q9H443
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:215 → 624
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272 → 292
    ZF_C2H2; C2H2 Zn finger [structural motif]

  40. NM_001387304.1 → NP_001374233.1  zinc finger protein 133 isoform c

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS63234.1
    UniProtKB/Swiss-Prot
    A8K5S4, B4DHU7, B4DIB8, B7ZAS1, F5H289, J3KQ11, J3KQJ0, P52736, Q53XU1, Q5JXV8, Q9BUV2, Q9H443
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:215 → 624
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272 → 292
    ZF_C2H2; C2H2 Zn finger [structural motif]

  41. NM_001387305.1 → NP_001374234.1  zinc finger protein 133 isoform c

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS63234.1
    UniProtKB/Swiss-Prot
    A8K5S4, B4DHU7, B4DIB8, B7ZAS1, F5H289, J3KQ11, J3KQJ0, P52736, Q53XU1, Q5JXV8, Q9BUV2, Q9H443
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:215 → 624
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272 → 292
    ZF_C2H2; C2H2 Zn finger [structural motif]

  42. NM_001387306.1 → NP_001374235.1  zinc finger protein 133 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS13134.1
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:214 → 623
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:271 → 291
    ZF_C2H2; C2H2 Zn finger [structural motif]

  43. NM_001387307.1 → NP_001374236.1  zinc finger protein 133 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS13134.1
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:214 → 623
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:271 → 291
    ZF_C2H2; C2H2 Zn finger [structural motif]

  44. NM_001387308.1 → NP_001374237.1  zinc finger protein 133 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS13134.1
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:214 → 623
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:271 → 291
    ZF_C2H2; C2H2 Zn finger [structural motif]

  45. NM_001387309.1 → NP_001374238.1  zinc finger protein 133 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS13134.1
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:214 → 623
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:271 → 291
    ZF_C2H2; C2H2 Zn finger [structural motif]

  46. NM_001387310.1 → NP_001374239.1  zinc finger protein 133 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS13134.1
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:214 → 623
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:271 → 291
    ZF_C2H2; C2H2 Zn finger [structural motif]

  47. NM_001387311.1 → NP_001374240.1  zinc finger protein 133 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS13134.1
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:214 → 623
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:271 → 291
    ZF_C2H2; C2H2 Zn finger [structural motif]

  48. NM_001387312.1 → NP_001374241.1  zinc finger protein 133 isoform o

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Conserved Domains (3) summary
    smart00349
    Location:1 → 53
    KRAB; krueppel associated box
    COG5048
    Location:208 → 617
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:265 → 285
    ZF_C2H2; C2H2 Zn finger [structural motif]

  49. NM_001387313.1 → NP_001374242.1  zinc finger protein 133 isoform p

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Conserved Domains (2) summary
    COG5048
    Location:183 → 592
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:240 → 260
    ZF_C2H2; C2H2 Zn finger [structural motif]

  50. NM_001387314.1 → NP_001374243.1  zinc finger protein 133 isoform q

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Conserved Domains (2) summary
    COG5048
    Location:182 → 591
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:239 → 259
    ZF_C2H2; C2H2 Zn finger [structural motif]

  51. NM_001387315.1 → NP_001374244.1  zinc finger protein 133 isoform e

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Conserved Domains (2) summary
    COG5048
    Location:152 → 561
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:209 → 229
    ZF_C2H2; C2H2 Zn finger [structural motif]

  52. NM_001387316.1 → NP_001374245.1  zinc finger protein 133 isoform e

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Conserved Domains (2) summary
    COG5048
    Location:152 → 561
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:209 → 229
    ZF_C2H2; C2H2 Zn finger [structural motif]

  53. NM_001387317.1 → NP_001374246.1  zinc finger protein 133 isoform e

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Conserved Domains (2) summary
    COG5048
    Location:152 → 561
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:209 → 229
    ZF_C2H2; C2H2 Zn finger [structural motif]

  54. NM_001387318.1 → NP_001374247.1  zinc finger protein 133 isoform e

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Conserved Domains (2) summary
    COG5048
    Location:152 → 561
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:209 → 229
    ZF_C2H2; C2H2 Zn finger [structural motif]

  55. NM_001387319.1 → NP_001374248.1  zinc finger protein 133 isoform k

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Conserved Domains (2) summary
    COG5048
    Location:151 → 560
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:208 → 228
    ZF_C2H2; C2H2 Zn finger [structural motif]

  56. NM_001387320.1 → NP_001374249.1  zinc finger protein 133 isoform i

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS74703.2
    Conserved Domains (2) summary
    COG5048
    Location:120 → 529
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:177 → 197
    ZF_C2H2; C2H2 Zn finger [structural motif]

  57. NM_001387321.1 → NP_001374250.1  zinc finger protein 133 isoform i

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS74703.2
    Conserved Domains (2) summary
    COG5048
    Location:120 → 529
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:177 → 197
    ZF_C2H2; C2H2 Zn finger [structural motif]

  58. NM_003434.7 → NP_003425.3  zinc finger protein 133 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL049646
    Consensus CDS
    CCDS13134.1
    Related
    ENSP00000366899.3, ENST00000377671.7
    Conserved Domains (3) summary
    smart00349
    Location:1 → 60
    KRAB; krueppel associated box
    COG5048
    Location:214 → 623
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:271 → 291
    ZF_C2H2; C2H2 Zn finger [structural motif]

RNA

  1. NR_178036.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    CP068258

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

    Range
    18288527..18316996
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060944.1 Alternate T2T-CHM13v2.0

    Range
    18339617..18368084
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P52736.2 GenPept UniProtKB/Swiss-Prot:P52736

Gene LinkOut

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