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Mir142hg Mir142 host gene (non-protein coding) [ Mus musculus (house mouse) ]

Gene ID: 78591, updated on 16-Apr-2024

Summary

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Official Symbol
Mir142hgprovided by MGI
Official Full Name
Mir142 host gene (non-protein coding)provided by MGI
Primary source
MGI:MGI:1925841
See related
AllianceGenome:MGI:1925841
Gene type
protein coding
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
A430104N18Rik
Summary
Acts upstream of or within dendritic cell homeostasis. Is expressed in lung. [provided by Alliance of Genome Resources, Apr 2022]
Annotation information
not in current annotation release
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Genomic context

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Location:
11 52.21 cM

Bibliography

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Related articles in PubMed

  1. MiR-142-3p regulates synaptopathy-driven disease progression in multiple sclerosis. De Vito F, et al. Neuropathol Appl Neurobiol, 2022 Feb. PMID 34490928, Free PMC Article
  2. MicroRNA-142-3p facilitates inflammatory response by targeting ZEB2 and activating NF-κB signaling in gouty arthritis. Lu Y, et al. Cell Cycle, 2022 Apr. PMID 35239453, Free PMC Article
  3. miR-142 orchestrates a network of actin cytoskeleton regulators during megakaryopoiesis. Chapnik E, et al. Elife, 2014 May 23. PMID 24859754, Free PMC Article
  4. RNA viruses can hijack vertebrate microRNAs to suppress innate immunity. Trobaugh DW, et al. Nature, 2014 Feb 13. PMID 24352241, Free PMC Article
  5. Mononuclear phagocyte miRNome analysis identifies miR-142 as critical regulator of murine dendritic cell homeostasis. Mildner A, et al. Blood, 2013 Feb 7. PMID 23212522

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. MicroRNA-142-3p facilitates inflammatory response by targeting ZEB2 and activating NF-kappaB signaling in gouty arthritis.
    Title: MicroRNA-142-3p facilitates inflammatory response by targeting ZEB2 and activating NF-κB signaling in gouty arthritis.
  2. results suggest that the glucocorticoid-miR-142-Ep300-beta-catenin signaling axis controls pneumocyte maturation
    Title: A critical role for miR-142 in alveolar epithelial lineage formation in mouse lung development.
  3. Significantly lower miR-142-3p levels were observed in plasma MP of Cd39 null mice after partial hepatectomy
    Title: Mononuclear-cell-derived microparticles attenuate endothelial inflammation by transfer of miR-142-3p in a CD39 dependent manner.
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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 

General gene information

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Markers

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within dendritic cell homeostasis IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

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Preferred Names
uncharacterized protein LOC78591
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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