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rhcgb Rh family, C glycoprotein b [ Danio rerio (zebrafish) ]

Gene ID: 792274, updated on 2-Nov-2024

Summary

Official Symbol
rhcgbprovided by ZNC
Official Full Name
Rh family, C glycoprotein bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2595
See related
Ensembl:ENSDARG00000100265 AllianceGenome:ZFIN:ZDB-GENE-040426-2595
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
rhcg; rhcgl2; zgc:77520
Summary
Predicted to enable ammonium channel activity. Acts upstream of or within ammonium homeostasis and ammonium transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in gill; immune system; integument; and yolk. Orthologous to human RHCG (Rh family C glycoprotein). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See rhcgb in Genome Data Viewer
Location:
chromosome: 25
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (8580941..8602460, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (8503873..8525460, complement)

Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101885510 Neighboring gene uncharacterized LOC137489327 Neighboring gene microRNA 9-3 Neighboring gene GDP-D-glucose phosphorylase 1 Neighboring gene unc-45 myosin chaperone A

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Clone Names

  • MGC77520

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ammonium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ammonium channel activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in ammonium homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within ammonium homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in ammonium transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within ammonium transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within ammonium transmembrane transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ammonium transporter Rh type C-like 2
Names
Rhesus blood group, C glycoprotein b
drRhcg1
rh family type C glycoprotein-like 2
rhesus blood group family type C glycoprotein-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001320382.1NP_001307311.1  ammonium transporter Rh type C-like 2

    Status: VALIDATED

    Source sequence(s)
    CK024807, CU633616, EH442849, EH468730
    UniProtKB/Swiss-Prot
    A5LHA7, Q6NYR3, Q8JI14
    UniProtKB/TrEMBL
    A0A0R4IBV5, A0A8M1P2Z1
    Related
    ENSDARP00000131256.1, ENSDART00000171200.2
    Conserved Domains (1) summary
    cl03012
    Location:73432
    Ammonium_transp; Ammonium Transporter Family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007136.7 Reference GRCz11 Primary Assembly

    Range
    8580941..8602460 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017354103.3XP_017209592.2  ammonium transporter Rh type C-like 2 isoform X1

    UniProtKB/Swiss-Prot
    A5LHA7, Q6NYR3, Q8JI14
    UniProtKB/TrEMBL
    A0A8M6Z506
    Conserved Domains (1) summary
    cl03012
    Location:73422
    Ammonium_transp; Ammonium Transporter Family

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_207082.1: Suppressed sequence

    Description
    NM_207082.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.