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edf1 endothelial differentiation-related factor 1 [ Danio rerio (zebrafish) ]

Gene ID: 793036, updated on 2-Nov-2024

Summary

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Official Symbol
edf1provided by ZNC
Official Full Name
endothelial differentiation-related factor 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1710
See related
Ensembl:ENSDARG00000009950 AllianceGenome:ZFIN:ZDB-GENE-040426-1710
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:73192; zgc:86829
Summary
Predicted to enable DNA binding activity. Predicted to be active in nucleus. Orthologous to human EDF1 (endothelial differentiation related factor 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See edf1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (64397643..64406058)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (63716479..63724894)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103911142 Neighboring gene phospholipid phosphatase 7a (inactive) Neighboring gene BRD3 opposite strand Neighboring gene bromodomain containing 3b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC73192, MGC86829

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
endothelial differentiation-related factor 1 homolog
Names
EDF-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200745.1 → NP_957039.1  endothelial differentiation-related factor 1 homolog

    See identical proteins and their annotated locations for NP_957039.1

    Status: PROVISIONAL

    Source sequence(s)
    BC059541
    UniProtKB/Swiss-Prot
    Q6PBY3
    UniProtKB/TrEMBL
    A5PN46
    Related
    ENSDARP00000026769.5, ENSDART00000015940.7
    Conserved Domains (2) summary
    smart00530
    Location:80 → 132
    HTH_XRE; Helix-turn-helix XRE-family like proteins
    pfam08523
    Location:4 → 71
    MBF1; Multiprotein bridging factor 1

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    64397643..64406058
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6PBY3.1 GenPept UniProtKB/Swiss-Prot:Q6PBY3

Gene LinkOut

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