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Klra23 killer cell lectin-like receptor subfamily A, member 23 [ Mus musculus (house mouse) ]

Gene ID: 79410, updated on 9-Dec-2024

Summary

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Official Symbol
Klra23provided by MGI
Official Full Name
killer cell lectin-like receptor subfamily A, member 23provided by MGI
Primary source
MGI:MGI:1930932
See related
AllianceGenome:MGI:1930932
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ly49W; Ly-49W1; Ly-49W2
Summary
Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
Annotation information
not in current annotation release
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Genomic context

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See Klra23 in Genome Data Viewer
Location:
6; 6 F3
Annotation release Status Assembly Chr Location
108.20200622 latest, but not current GRCm38.p6 (GCF_000001635.26) 6 Unlocalized Scaffold (NOD/ShiLtJ) NT_187002.1 (553984..576907, complement)

Bibliography

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Related articles in PubMed

  1. The activating Ly49W and inhibitory Ly49G NK cell receptors display similar affinities for identical MHC class I ligands. Ma BJ, et al. Immunogenetics, 2014 Aug. PMID 24797174
  2. Ly-49W, an activating receptor of nonobese diabetic mice with close homology to the inhibitory receptor Ly-49G, recognizes H-2D(k) and H-2D(d). Silver ET, et al. J Immunol, 2001 Feb 15. PMID 11160290
  3. Class I MHC-binding characteristics of the 129/J Ly49 repertoire. Makrigiannis AP, et al. J Immunol, 2001 Apr 15. PMID 11290784
  4. The ly49 gene family. A brief guide to the nomenclature, genetics, and role in intracellular infection. Schenkel AR, et al. Front Immunol, 2013. PMID 23596445, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The ectodomain of inhibitory Ly49G of the BALB/c mouse strain is highly similar to the Ly49W activating receptor in the nonobese diabetic (NOD) mouse.
    Title: The activating Ly49W and inhibitory Ly49G NK cell receptors display similar affinities for identical MHC class I ligands.
Submit: New GeneRIF Correction

General gene information

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Markers

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in plasma membrane TAS
Traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
killer cell lectin-like receptor subfamily A, member 23
Names
killer cell lectin-like receptor subfamily A, member 17

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024470.1 → NP_077790.1  killer cell lectin-like receptor subfamily A, member 23

    See identical proteins and their annotated locations for NP_077790.1

    Status: PROVISIONAL

    Source sequence(s)
    AF074459
    UniProtKB/TrEMBL
    Q9EP57, Q9EPB2
    Conserved Domains (2) summary
    cd03593
    Location:146 → 261
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
    pfam08391
    Location:40 → 159
    Ly49; Ly49-like protein, N-terminal region
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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