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atrn attractin [ Danio rerio (zebrafish) ]

Gene ID: 794975, updated on 4-Jan-2025

Summary

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Official Symbol
atrnprovided by ZNC
Official Full Name
attractinprovided by ZNC
Primary source
ZFIN:ZDB-GENE-090312-21
See related
Ensembl:ENSDARG00000062164 AllianceGenome:ZFIN:ZDB-GENE-090312-21
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-259n11.1
Summary
Predicted to enable chromatin binding activity. Acts upstream of or within regulation of actomyosin structure organization. Predicted to be located in membrane. Predicted to be active in cytoplasm. Is expressed in blastomere; forebrain; midbrain; and otic vesicle. Orthologous to human ATRN (attractin). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
human mouse all
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Genomic context

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See atrn in Genome Data Viewer
Location:
chromosome: 13
Exon count:
29
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (14006133..14181765)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (13875331..14048438)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 2-alpha kinase 3 Neighboring gene ribose 5-phosphate isomerase A (ribose 5-phosphate epimerase) Neighboring gene uncharacterized LOC101884819 Neighboring gene GDNF family receptor alpha 4a Neighboring gene uncharacterized LOC137487375

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Attractin Participates in Schizophrenia by Affecting Testosterone Levels. Li N, et al. Front Cell Dev Biol, 2021. PMID 34869343, Free PMC Article
  2. Alkbh4 and Atrn Act Maternally to Regulate Zebrafish Epiboly. Sun Q, et al. Int J Biol Sci, 2017. PMID 28924386, Free PMC Article
  3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of actomyosin structure organization IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within regulation of actomyosin structure organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
attractin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001353962.1 → NP_001340891.1  attractin

    Status: VALIDATED

    Source sequence(s)
    CR388098, CR589874, CT583702
    UniProtKB/TrEMBL
    A0A8N1Z1N4, B8JI13
    Related
    ENSDARP00000083961.7, ENSDART00000089528.7
    Conserved Domains (8) summary
    cd03597
    Location:740 → 869
    CLECT_attractin_like; C-type lectin-like domain (CTLD) of the type found in human and mouse attractin (AtrN) and attractin-like protein (ALP)
    cd00041
    Location:83 → 197
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00055
    Location:1016 → 1061
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    sd00038
    Location:506 → 563
    Kelch; KELCH repeat [structural motif]
    pfam01344
    Location:506 → 558
    Kelch_1; Kelch motif
    pfam01437
    Location:881 → 932
    PSI; Plexin repeat
    pfam13418
    Location:453 → 496
    Kelch_4; Galactose oxidase, central domain
    cl28614
    Location:291 → 440
    BTB; Broad-Complex, Tramtrack and Bric a brac

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    14006133..14181765
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394873.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    236087..418369
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001145615.1: Suppressed sequence

    Description
    NM_001145615.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein
Heading Accession and Version

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