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NTNG2 netrin G2 [ Homo sapiens (human) ]

Gene ID: 84628, updated on 2-Nov-2024

Summary

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Official Symbol
NTNG2provided by HGNC
Official Full Name
netrin G2provided by HGNC
Primary source
HGNC:HGNC:14288
See related
Ensembl:ENSG00000196358 MIM:618689; AllianceGenome:HGNC:14288
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Lmnt2; NTNG1; NEDBASH; LHLL9381; NetrinG2; bA479K20.1
Summary
Predicted to be involved in axonogenesis; regulation of cell projection organization; and regulation of neuron migration. Predicted to be located in plasma membrane. Predicted to be active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and presynaptic active zone membrane. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in bone marrow (RPKM 7.5), brain (RPKM 4.1) and 4 other tissues See more
Orthologs
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Genomic context

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See NTNG2 in Genome Data Viewer
Location:
9q34.13
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (132161689..132244526)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (144375733..144459025)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (135037445..135119913)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:134752115-134752615 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:134764767-134765298 Neighboring gene Sharpr-MPRA regulatory region 801 Neighboring gene mediator complex subunit 27 Neighboring gene NANOG hESC enhancer GRCh37_chr9:134840462-134840963 Neighboring gene ReSE screen-validated silencer GRCh37_chr9:134843516-134843723 Neighboring gene MPRA-validated peak7336 silencer Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr9:134882251-134882943 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:134915689-134916190 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr9:134917173-134918372 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:134916191-134916690 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr9:134951028-134952227 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29216 Neighboring gene uncharacterized LOC105376302 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:135004636-135005136 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:135005137-135005637 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:135011939-135012452 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:135029860-135030360 Neighboring gene uncharacterized LOC124902291 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:135044919-135045676 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:135045677-135046434 Neighboring gene Sharpr-MPRA regulatory region 1592 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:135061794-135062407 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:135082729-135083404 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:135083405-135084080 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:135089048-135089792 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:135115111-135115628 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20426 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20427 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20428 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:135120407-135120912 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:135120913-135121418 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr9:135144739-135145938 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:135171222-135171722 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:135171723-135172223 Neighboring gene senataxin Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29217 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr9:135229958-135231157 Neighboring gene Sharpr-MPRA regulatory region 6614 Neighboring gene uncharacterized LOC124902292 Neighboring gene transcription termination factor 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Homozygous Missense Variants in NTNG2, Encoding a Presynaptic Netrin-G2 Adhesion Protein, Lead to a Distinct Neurodevelopmental Disorder. Dias CM, et al. Am J Hum Genet, 2019 Nov 7. PMID 31668703, Free PMC Article
  2. Homozygous frameshift variant in NTNG2, encoding a synaptic cell adhesion molecule, in individuals with developmental delay, hypotonia, and autistic features. Abu-Libdeh B, et al. Neurogenetics, 2019 Oct. PMID 31372774
  3. Crystal structure of the ligand binding domain of netrin G2. Brasch J, et al. J Mol Biol, 2011 Dec 16. PMID 22041449, Free PMC Article
  4. A family-based association study and gene expression analyses of netrin-G1 and -G2 genes in schizophrenia. Aoki-Suzuki M, et al. Biol Psychiatry, 2005 Feb 15. PMID 15705354
  5. Human netrin-G1 isoforms show evidence of differential expression. Meerabux JM, et al. Genomics, 2005 Jul. PMID 15901489

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Netrin-G2 dysfunction causes a Rett-like phenotype with areflexia.
    Title: Netrin-G2 dysfunction causes a Rett-like phenotype with areflexia.
  2. Homozygous frameshift variant in NTNG2, encoding a synaptic cell adhesion molecule, in individuals with developmental delay, hypotonia, and autistic features.
    Title: Homozygous frameshift variant in NTNG2, encoding a synaptic cell adhesion molecule, in individuals with developmental delay, hypotonia, and autistic features.
  3. Appropriate expression of NTNG2 plays an important role in neurotypical development.
    Title: Homozygous Missense Variants in NTNG2, Encoding a Presynaptic Netrin-G2 Adhesion Protein, Lead to a Distinct Neurodevelopmental Disorder.
  4. presence of Gng2 and Netrin-G2 immunoreactive elements in the insular cortex, but not in the putamen, suggests a possible common ontogeny of the claustrum and insula
    Title: Topography of Gng2- and NetrinG2-expression suggests an insular origin of the human claustrum.
  5. the crystal structure for a fragment comprising the LN domain and domain LE1 of netrin G2 by sulfur single-wavelength anomalous diffraction phasing and refined it to 1.8 A resolution was determined.
    Title: Crystal structure of the ligand binding domain of netrin G2.
  6. Netrin-g2 is involved in the pathophysiology of epilepsy and are consistent with the hypothesis that this protein may participate in the abnormal development of synapses and in neuron migration
    Title: Abnormal expression of netrin-G2 in temporal lobe epilepsy neurons in humans and a rat model.
  7. Observational study of gene-disease association. (HuGE Navigator)
    Title: Association of polymorphisms in the SLIT2 axonal guidance gene with anger in suicide attempters.
  8. The data of this stusty implicate NTNG2 in the pathophysiology of schizophrenia and bipolar disorder, but do not support the hypothesis that altered mRNA expression is the mechanism by which genetic variation of NTNG2 may confer disease susceptibility.
    Title: Decreased mRNA expression of netrin-G1 and netrin-G2 in the temporal lobe in schizophrenia and bipolar disorder.
  9. An association between NTNG2 and schizophrenia was observed with SNPs and haplotypes that clustered in the 5' region of the gene.
    Title: A family-based association study and gene expression analyses of netrin-G1 and -G2 genes in schizophrenia.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description Tests
Neurodevelopmental disorder with behavioral abnormalities, absent speech, and hypotonia
MedGen: C5231471 OMIM: 618718 GeneReviews: Not available
not available

EBI GWAS Catalog

Description
Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • KIAA0625, KIAA1857, MGC21884

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in axonogenesis ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in modulation of chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
  
involved_in postsynaptic specialization assembly IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of neuron migration ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of neuron projection arborization ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of neuron projection development ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of presynapse assembly IEA
Inferred from Electronic Annotation
more info
  
involved_in synaptic membrane adhesion IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Schaffer collateral - CA1 synapse IEA
Inferred from Electronic Annotation
more info
  
located_in axon IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular region TAS
Traceable Author Statement
more info
  
located_in glutamatergic synapse IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in plasma membrane TAS
Traceable Author Statement
more info
  
located_in presynaptic active zone membrane IEA
Inferred from Electronic Annotation
more info
  
located_in side of membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
netrin-G2
Names
laminet 2
netrin G1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032536.4 → NP_115925.2  netrin-G2 precursor

    See identical proteins and their annotated locations for NP_115925.2

    Status: VALIDATED

    Source sequence(s)
    AL159997, AL353631, CK301008
    Consensus CDS
    CCDS6946.1
    UniProtKB/Swiss-Prot
    Q5JUJ2, Q6UXY0, Q96CW9, Q96JH0
    Related
    ENSP00000376921.3, ENST00000393229.4
    Conserved Domains (3) summary
    cd00055
    Location:286 → 332
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:409 → 456
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:60 → 285
    Laminin_N; Laminin N-terminal (Domain VI)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    132161689..132244526
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011519096.3 → XP_011517398.1  netrin-G2 isoform X1

    See identical proteins and their annotated locations for XP_011517398.1

    Conserved Domains (4) summary
    cd00055
    Location:286 → 332
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:515 → 562
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:60 → 285
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam07974
    Location:562 → 592
    EGF_2; EGF-like domain

  2. XM_017015213.2 → XP_016870702.1  netrin-G2 isoform X1

    Conserved Domains (4) summary
    cd00055
    Location:286 → 332
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:515 → 562
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:60 → 285
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam07974
    Location:562 → 592
    EGF_2; EGF-like domain

  3. XM_047423970.1 → XP_047279926.1  netrin-G2 isoform X1

  4. XM_017015212.2 → XP_016870701.1  netrin-G2 isoform X1

    Conserved Domains (4) summary
    cd00055
    Location:286 → 332
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:515 → 562
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:60 → 285
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam07974
    Location:562 → 592
    EGF_2; EGF-like domain

  5. XM_011519094.3 → XP_011517396.1  netrin-G2 isoform X1

    See identical proteins and their annotated locations for XP_011517396.1

    Conserved Domains (4) summary
    cd00055
    Location:286 → 332
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:515 → 562
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:60 → 285
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam07974
    Location:562 → 592
    EGF_2; EGF-like domain

  6. XM_011519106.3 → XP_011517408.1  netrin-G2 isoform X2

    Conserved Domains (4) summary
    cd00055
    Location:286 → 332
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:492 → 539
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:60 → 285
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam07974
    Location:539 → 569
    EGF_2; EGF-like domain

  7. XM_006717304.4 → XP_006717367.1  netrin-G2 isoform X3

    Conserved Domains (4) summary
    cd00055
    Location:286 → 332
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:443 → 490
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:60 → 285
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam07974
    Location:490 → 520
    EGF_2; EGF-like domain

  8. XM_011519107.3 → XP_011517409.1  netrin-G2 isoform X4

    See identical proteins and their annotated locations for XP_011517409.1

    UniProtKB/Swiss-Prot
    Q5JUJ2, Q6UXY0, Q96CW9, Q96JH0
    Conserved Domains (3) summary
    cd00055
    Location:286 → 332
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:409 → 456
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:60 → 285
    Laminin_N; Laminin N-terminal (Domain VI)

  9. XM_011519098.3 → XP_011517400.1  netrin-G2 isoform X1

    See identical proteins and their annotated locations for XP_011517400.1

    Conserved Domains (4) summary
    cd00055
    Location:286 → 332
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:515 → 562
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:60 → 285
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam07974
    Location:562 → 592
    EGF_2; EGF-like domain

  10. XM_011519102.3 → XP_011517404.1  netrin-G2 isoform X1

    See identical proteins and their annotated locations for XP_011517404.1

    Conserved Domains (4) summary
    cd00055
    Location:286 → 332
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:515 → 562
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:60 → 285
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam07974
    Location:562 → 592
    EGF_2; EGF-like domain

  11. XM_011519097.4 → XP_011517399.1  netrin-G2 isoform X1

    See identical proteins and their annotated locations for XP_011517399.1

    Conserved Domains (4) summary
    cd00055
    Location:286 → 332
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:515 → 562
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:60 → 285
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam07974
    Location:562 → 592
    EGF_2; EGF-like domain

  12. XM_011519099.3 → XP_011517401.1  netrin-G2 isoform X1

    See identical proteins and their annotated locations for XP_011517401.1

    Conserved Domains (4) summary
    cd00055
    Location:286 → 332
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:515 → 562
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:60 → 285
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam07974
    Location:562 → 592
    EGF_2; EGF-like domain

  13. XM_011519100.3 → XP_011517402.1  netrin-G2 isoform X1

    See identical proteins and their annotated locations for XP_011517402.1

    Conserved Domains (4) summary
    cd00055
    Location:286 → 332
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:515 → 562
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:60 → 285
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam07974
    Location:562 → 592
    EGF_2; EGF-like domain

  14. XM_011519108.3 → XP_011517410.1  netrin-G2 isoform X5

    Conserved Domains (2) summary
    cd00055
    Location:286 → 332
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00055
    Location:60 → 285
    Laminin_N; Laminin N-terminal (Domain VI)

  15. XM_011519109.3 → XP_011517411.1  netrin-G2 isoform X6

    Conserved Domains (2) summary
    cd00055
    Location:286 → 332
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00055
    Location:60 → 285
    Laminin_N; Laminin N-terminal (Domain VI)

  16. XM_011519110.3 → XP_011517412.1  netrin-G2 isoform X7

    Conserved Domains (2) summary
    cd00055
    Location:286 → 332
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00055
    Location:60 → 285
    Laminin_N; Laminin N-terminal (Domain VI)

  17. XM_017015216.2 → XP_016870705.1  netrin-G2 isoform X9

  18. XM_011519105.3 → XP_011517407.1  netrin-G2 isoform X1

    See identical proteins and their annotated locations for XP_011517407.1

    Conserved Domains (4) summary
    cd00055
    Location:286 → 332
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:515 → 562
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:60 → 285
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam07974
    Location:562 → 592
    EGF_2; EGF-like domain

  19. XM_047423971.1 → XP_047279927.1  netrin-G2 isoform X1

  20. XM_011519104.4 → XP_011517406.1  netrin-G2 isoform X1

    See identical proteins and their annotated locations for XP_011517406.1

    Conserved Domains (4) summary
    cd00055
    Location:286 → 332
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:515 → 562
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:60 → 285
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam07974
    Location:562 → 592
    EGF_2; EGF-like domain

  21. XM_011519103.3 → XP_011517405.1  netrin-G2 isoform X1

    See identical proteins and their annotated locations for XP_011517405.1

    Conserved Domains (4) summary
    cd00055
    Location:286 → 332
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:515 → 562
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:60 → 285
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam07974
    Location:562 → 592
    EGF_2; EGF-like domain

  22. XM_011519112.3 → XP_011517414.1  netrin-G2 isoform X8

    Conserved Domains (1) summary
    pfam00053
    Location:184 → 231
    Laminin_EGF; Laminin EGF domain

  23. XM_011519113.3 → XP_011517415.1  netrin-G2 isoform X10

    Conserved Domains (1) summary
    pfam00053
    Location:161 → 208
    Laminin_EGF; Laminin EGF domain

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    144375733..144459025
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054363989.1 → XP_054219964.1  netrin-G2 isoform X1

  2. XM_054363993.1 → XP_054219968.1  netrin-G2 isoform X1

  3. XM_054363994.1 → XP_054219969.1  netrin-G2 isoform X1

  4. XM_054363988.1 → XP_054219963.1  netrin-G2 isoform X1

  5. XM_054363986.1 → XP_054219961.1  netrin-G2 isoform X1

  6. XM_054364000.1 → XP_054219975.1  netrin-G2 isoform X2

  7. XM_054364002.1 → XP_054219977.1  netrin-G2 isoform X12

  8. XM_054364001.1 → XP_054219976.1  netrin-G2 isoform X11

  9. XM_054364003.1 → XP_054219978.1  netrin-G2 isoform X3

  10. XM_054364004.1 → XP_054219979.1  netrin-G2 isoform X4

  11. XM_054363992.1 → XP_054219967.1  netrin-G2 isoform X1

  12. XM_054363995.1 → XP_054219970.1  netrin-G2 isoform X1

  13. XM_054363991.1 → XP_054219966.1  netrin-G2 isoform X1

  14. XM_054363987.1 → XP_054219962.1  netrin-G2 isoform X1

  15. XM_054363990.1 → XP_054219965.1  netrin-G2 isoform X1

  16. XM_054364005.1 → XP_054219980.1  netrin-G2 isoform X5

  17. XM_054364008.1 → XP_054219983.1  netrin-G2 isoform X6

  18. XM_054364010.1 → XP_054219985.1  netrin-G2 isoform X16

  19. XM_054364011.1 → XP_054219986.1  netrin-G2 isoform X7

  20. XM_054364007.1 → XP_054219982.1  netrin-G2 isoform X14

  21. XM_054364012.1 → XP_054219987.1  netrin-G2 isoform X9

  22. XM_054363997.1 → XP_054219972.1  netrin-G2 isoform X1

  23. XM_054363998.1 → XP_054219973.1  netrin-G2 isoform X1

  24. XM_054363999.1 → XP_054219974.1  netrin-G2 isoform X1

  25. XM_054363996.1 → XP_054219971.1  netrin-G2 isoform X1

  26. XM_054364009.1 → XP_054219984.1  netrin-G2 isoform X15

  27. XM_054364006.1 → XP_054219981.1  netrin-G2 isoform X13

RNA

  1. XR_008488085.1 RNA Sequence

  2. XR_008488084.1 RNA Sequence

  3. XR_008488083.1 RNA Sequence

  4. XR_008488081.1 RNA Sequence

  5. XR_008488082.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q96CW9.2 GenPept UniProtKB/Swiss-Prot:Q96CW9

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