U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

RLP24 [ Saccharomyces cerevisiae S288C ]

Gene ID: 850695, updated on 11-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
RLP24
Primary source
SGD:S000003999
Locus tag
YLR009W
See related
AllianceGenome:SGD:S000003999; FungiDB:YLR009W; VEuPathDB:YLR009W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables ATPase activator activity. Involved in assembly of large subunit precursor of preribosome and ribosomal large subunit biogenesis. Located in nucleolus. Part of preribosome, large subunit precursor. Orthologous to human RSL24D1 (ribosomal L24 domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (166537..167136)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Smc5-Smc6 complex subunit NSE1 Neighboring gene Pam18p Neighboring gene Ten1p Neighboring gene tRNA-Ser

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_001144.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The GTPase Nog1 co-ordinates the assembly, maturation and quality control of distant ribosomal functional centers. Klingauf-Nerurkar P, et al. Elife, 2020 Jan 7. PMID 31909713, Free PMC Article
  2. Cytoplasmic recycling of 60S preribosomal factors depends on the AAA protein Drg1. Pertschy B, et al. Mol Cell Biol, 2007 Oct. PMID 17646390, Free PMC Article
  3. Integrity of the P-site is probed during maturation of the 60S ribosomal subunit. Bussiere C, et al. J Cell Biol, 2012 Jun 11. PMID 22689654, Free PMC Article
  4. Nsa2 is an unstable, conserved factor required for the maturation of 27 SB pre-rRNAs. Lebreton A, et al. J Biol Chem, 2006 Sep 15. PMID 16861225
  5. Functional redundancy of yeast proteins Reh1 and Rei1 in cytoplasmic 60S subunit maturation. Parnell KM, et al. Mol Cell Biol, 2009 Jul. PMID 19433447, Free PMC Article

See all (88) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables ATPase activator activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in assembly of large subunit precursor of preribosome IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in ribosomal large subunit biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosomal large subunit biogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of preribosome, large subunit precursor HDA PubMed 
part_of preribosome, large subunit precursor IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
ATPase-activating ribosome biosynthesis protein
NP_013109.1
  • Essential protein required for ribosomal large subunit biogenesis; associated with pre-60S ribosomal subunits; stimulates the ATPase activity of Afg2p, which is required for release of Rlp24p from the pre-60S particle; has similarity to Rpl24Ap and Rpl24Bp

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    166537..167136
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181896.1 → NP_013109.1  TPA: ATPase-activating ribosome biosynthesis protein [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013109.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VY11, Q07915
    UniProtKB/TrEMBL
    A7A0R4, B3LSY2, B5VMV1, C7GPE9, C8ZCY1, G2WIK3, N1NYZ6
    Conserved Domains (1) summary
    pfam01246
    Location:2 → 64
    Ribosomal_L24e; Ribosomal protein L24e
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q07915.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools