U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

COQ11 ubiquinone biosynthesis protein COQ11 [ Saccharomyces cerevisiae S288C ]

Gene ID: 850997, updated on 1-Aug-2024

Summary

Go to the top of the page Help
Gene symbol
COQ11
Gene description
ubiquinone biosynthesis protein COQ11
Primary source
FungiDB:YLR290C
Locus tag
YLR290C
See related
SGD:S000004281; AllianceGenome:SGD:S000004281; VEuPathDB:YLR290C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
MRX2
Summary
Predicted to enable catalytic activity. Involved in ubiquinone-6 biosynthetic process. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See COQ11 in Genome Data Viewer
Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (717145..717978, complement)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Mec3p Neighboring gene GTPase GUF1 Neighboring gene translation initiation factor eIF2B subunit beta Neighboring gene Sec63 complex subunit SEC72

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_001144.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. COQ11 deletion mitigates respiratory deficiency caused by mutations in the gene encoding the coenzyme Q chaperone protein Coq10. Bradley MC, et al. J Biol Chem, 2020 May 1. PMID 32205446, Free PMC Article
  2. Coenzyme Q biosynthetic proteins assemble in a substrate-dependent manner into domains at ER-mitochondria contacts. Subramanian K, et al. J Cell Biol, 2019 Apr 1. PMID 30674579, Free PMC Article
  3. Functional genetic discovery of enzymes using full-scan mass spectrometry metabolomics (1). Caudy AA, et al. Biochem Cell Biol, 2019 Feb. PMID 30001498
  4. Assessing systems properties of yeast mitochondria through an interaction map of the organelle. Perocchi F, et al. PLoS Genet, 2006 Oct 20. PMID 17054397, Free PMC Article
  5. Identification of Coq11, a new coenzyme Q biosynthetic protein in the CoQ-synthome in Saccharomyces cerevisiae. Allan CM, et al. J Biol Chem, 2015 Mar 20. PMID 25631044, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. COQ11 deletion mitigates respiratory deficiency caused by mutations in the gene encoding the coenzyme Q chaperone protein Coq10.
    Title: COQ11 deletion mitigates respiratory deficiency caused by mutations in the gene encoding the coenzyme Q chaperone protein Coq10.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables protein-containing complex binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in ubiquinone biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in ubiquinone-6 biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ubiquinone-6 biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
ubiquinone biosynthesis protein COQ11
NP_013393.1
  • Putative oxidoreductase, subunit of Coenzyme Q biosynthetic complexes; required for synthesis of wild-type levels of Coenzyme Q (ubiquinone); member of the short-chain dehydrogenase/reductase (SDR) superfamily; orthologous gene in some other fungi is fused to the COQ10 ortholog

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    717145..717978 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182178.1 → NP_013393.1  TPA: ubiquinone biosynthesis protein COQ11 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013393.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VYT6, Q05892
    UniProtKB/TrEMBL
    A7A1H3, B3RHH0, C7GVU7, C8ZDQ4, G2WJB4, N1P718
    Conserved Domains (2) summary
    COG0702
    Location:3 → 83
    YbjT; Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains [General function prediction only]
    cl21454
    Location:7 → 204
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q05892.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools