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RPL26A ribosomal 60S subunit protein L26A [ Saccharomyces cerevisiae S288C ]

Gene ID: 851058, updated on 4-Aug-2024

Summary

Gene symbol
RPL26A
Gene description
ribosomal 60S subunit protein L26A
Primary source
FungiDB:YLR344W
Locus tag
YLR344W
See related
SGD:S000004336; AllianceGenome:SGD:S000004336; VEuPathDB:YLR344W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables RNA binding activity. A structural constituent of ribosome. Involved in cytoplasmic translation. Part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 11. Orthologous to human RPL26 (ribosomal protein L26) and RPL26L1 (ribosomal protein L26 like 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See RPL26A in Genome Data Viewer
Location:
chromosome: XII
Exon count:
2
Sequence:
Chromosome: XII; NC_001144.5 (819312..820142)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene 1,3-beta-glucanosyltransferase Neighboring gene tRNA-Arg Neighboring gene bifunctional fructose-2,6-bisphosphate 2-phosphatase/6-phosphofructo-2-kinase Neighboring gene Cis1p

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cytoplasmic translation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in ribosomal large subunit biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in translation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
PubMed 
located_in intracellular organelle IEA
Inferred from Electronic Annotation
more info
 
part_of large ribosomal subunit IEA
Inferred from Electronic Annotation
more info
 
part_of protein-containing complex IEA
Inferred from Electronic Annotation
more info
 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 
located_in ribosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ribosomal 60S subunit protein L26A
NP_013448.1
  • Ribosomal 60S subunit protein L26A; binds to 5.8S rRNA; non-essential even when paralog is also deleted; deletion has minimal affections on ribosome biosynthesis; homologous to mammalian ribosomal protein L26 and bacterial L24; RPL26A has a paralog, RPL26B, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    819312..820142
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182233.1NP_013448.1  TPA: ribosomal 60S subunit protein L26A [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013448.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VYY3, P05743
    UniProtKB/TrEMBL
    C7GRX0, N1NZN4
    Conserved Domains (1) summary
    pfam16906
    Location:9122
    Ribosomal_L26; Ribosomal proteins L26 eukaryotic, L24P archaeal