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HBT1 Hbt1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851303, updated on 29-Jun-2024

Summary

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Gene symbol
HBT1
Gene description
Hbt1p
Primary source
FungiDB:YDL223C
Locus tag
YDL223C
See related
SGD:S000002382; AllianceGenome:SGD:S000002382; VEuPathDB:YDL223C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in cell morphogenesis involved in conjugation with cellular fusion. Located in mating projection. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See HBT1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (57265..60405, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene septin SHS1 Neighboring gene Whi4p Neighboring gene Fmp45p Neighboring gene telomere-binding protein CDC13

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Role of a ubiquitin-like modification in polarized morphogenesis. Dittmar GA, et al. Science, 2002 Mar 29. PMID 11923536
  2. Identification of an Hsp90 mutation that selectively disrupts cAMP/PKA signaling in Saccharomyces cerevisiae. Flom GA, et al. Curr Genet, 2012 Jun. PMID 22461145
  3. Genomic analysis of stationary-phase and exit in Saccharomyces cerevisiae: gene expression and identification of novel essential genes. Martinez MJ, et al. Mol Biol Cell, 2004 Dec. PMID 15456898, Free PMC Article
  4. The Lsm1-7/Pat1 complex binds to stress-activated mRNAs and modulates the response to hyperosmotic shock. Garre E, et al. PLoS Genet, 2018 Jul. PMID 30059503, Free PMC Article
  5. Dbf4-dependent CDC7 kinase links DNA replication to the segregation of homologous chromosomes in meiosis I. Matos J, et al. Cell, 2008 Nov 14. PMID 19013276

See all (43) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in cell morphogenesis involved in conjugation with cellular fusion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of cell shape IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in mating projection IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane HDA PubMed 

General protein information

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Preferred Names
Hbt1p
NP_010058.1
  • Shmoo tip protein, substrate of Hub1p ubiquitin-like protein; mutants are defective for mating projection formation, thereby implicating Hbt1p in polarized cell morphogenesis; HBT1 has a paralog, YNL195C, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    57265..60405 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180283.1 → NP_010058.1  TPA: Hbt1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010058.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VRD2, Q07653
    UniProtKB/TrEMBL
    A0A8H8UM80, C7GSV5, C8Z6P6, N1P7W2
    Conserved Domains (1) summary
    NF033849
    Location:168 → 343
    ser_rich_anae_1; serine-rich protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q07653.1

Gene LinkOut

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