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RPL4B ribosomal 60S subunit protein L4B [ Saccharomyces cerevisiae S288C ]

Gene ID: 851575, updated on 4-Aug-2024

Summary

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Gene symbol
RPL4B
Gene description
ribosomal 60S subunit protein L4B
Primary source
FungiDB:YDR012W
Locus tag
YDR012W
See related
SGD:S000002419; AllianceGenome:SGD:S000002419; VEuPathDB:YDR012W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Orthologous to human RPL4 (ribosomal protein L4). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See RPL4B in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (471853..472941)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ATP-binding cassette transporter SNQ2 Neighboring gene DNA replication protein PSF1 Neighboring gene Rad61p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sequencing and analysis of a 35.4 kb region on the right [corrected] arm of chromosome IV from Saccharomyces cerevisiae reveal 23 open reading frames. Eide LG, et al. Yeast, 1996 Sep. PMID 8896275
  2. Identification of the cis-elements mediating the autogenous control of ribosomal protein L2 mRNA stability in yeast. Presutti C, et al. EMBO J, 1995 Aug 15. PMID 7664741, Free PMC Article
  3. Gene dosage alteration of L2 ribosomal protein genes in Saccharomyces cerevisiae: effects on ribosome synthesis. Lucioli A, et al. Mol Cell Biol, 1988 Nov. PMID 3062369, Free PMC Article
  4. Ribosomal protein L2 in Saccharomyces cerevisiae is homologous to ribosomal protein L1 in Xenopus laevis. Isolation and characterization of the genes. Presutti C, et al. J Biol Chem, 1988 May 5. PMID 2834365
  5. The ribosomal protein L2 in S. cerevisiae controls the level of accumulation of its own mRNA. Presutti C, et al. EMBO J, 1991 Aug. PMID 2065661, Free PMC Article

See all (94) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IC
Inferred by Curator
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation IC
Inferred by Curator
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ribosomal 60S subunit protein L4B
NP_010295.3
  • Ribosomal 60S subunit protein L4B; homologous to mammalian ribosomal protein L4 and bacterial L4; RPL4B has a paralog, RPL4A, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    471853..472941
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180320.3 → NP_010295.3  TPA: ribosomal 60S subunit protein L4B [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010295.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VRZ8, P49626
    UniProtKB/TrEMBL
    A6ZXX7, B3LGP9, B3LNB3, C8Z4T1
    Conserved Domains (1) summary
    PTZ00428
    Location:2 → 350
    PTZ00428; 60S ribosomal protein L4; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P49626.2

Gene LinkOut

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