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ATP5 F1F0 ATP synthase subunit 5 [ Saccharomyces cerevisiae S288C ]

Gene ID: 851892, updated on 1-Aug-2024

Summary

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Gene symbol
ATP5
Gene description
F1F0 ATP synthase subunit 5
Primary source
FungiDB:YDR298C
Locus tag
YDR298C
See related
SGD:S000002706; AllianceGenome:SGD:S000002706; VEuPathDB:YDR298C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
OSC1
Summary
Contributes to proton-transporting ATP synthase activity, rotational mechanism. Involved in ATP synthesis coupled proton transport. Located in mitochondrion. Part of mitochondrial proton-transporting ATP synthase, stator stalk. Orthologous to human ATP5PO (ATP synthase peripheral stalk subunit OSCP). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See ATP5 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (1058176..1058814, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene mitochondrial 54S ribosomal protein MHR1 Neighboring gene sphingosine hydroxylase Neighboring gene rRNA-processing protein BFR2 Neighboring gene glutamate 5-kinase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Modulation at a distance of proton conductance through the Saccharomyces cerevisiae mitochondrial F1F0-ATP synthase by variants of the oligomycin sensitivity-conferring protein containing substitutions near the C-terminus. Boyle GM, et al. J Bioenerg Biomembr, 2000 Dec. PMID 15254373
  2. Structural interactions of the oligomycin sensitivity-conferring protein in the yeast ATP synthase. Mao Y, et al. Arch Biochem Biophys, 1997 Jan 1. PMID 8990262
  3. Level of ATP synthase activity required for yeast Saccharomyces cerevisiae to grow on glycerol media. Mukhopadhyay A, et al. FEBS Lett, 1994 Apr 25. PMID 8168623
  4. Properties of yeast cells depleted of the OSCP subunit of mitochondrial ATP synthase by regulated expression of the ATP5 gene. Prescott M, et al. Biochem Mol Biol Int, 1994 Oct. PMID 7866306
  5. The gene coding for the yeast oligomycin sensitivity-conferring protein. Uh M, et al. J Biol Chem, 1990 Nov 5. PMID 2146269

See all (74) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
contributes_to proton-transporting ATP synthase activity, rotational mechanism IBA
Inferred from Biological aspect of Ancestor
more info
  
contributes_to proton-transporting ATP synthase activity, rotational mechanism IDA
Inferred from Direct Assay
more info
 PubMed 
enables proton-transporting ATP synthase activity, rotational mechanism IEA
Inferred from Electronic Annotation
more info
  
contributes_to proton-transporting ATP synthase activity, rotational mechanism IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in ATP biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in proton motive force-driven ATP synthesis IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in proton motive force-driven ATP synthesis IEA
Inferred from Electronic Annotation
more info
  
involved_in proton motive force-driven ATP synthesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in proton motive force-driven mitochondrial ATP synthesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
part_of mitochondrial proton-transporting ATP synthase, stator stalk IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion HDA PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
part_of proton-transporting ATP synthase, stator stalk IDA
Inferred from Direct Assay
more info
 PubMed 
part_of proton-transporting ATP synthase, stator stalk IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

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Preferred Names
F1F0 ATP synthase subunit 5
NP_010584.1
  • Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase; F1F0 ATP synthase is a large, evolutionarily conserved enzyme complex required for ATP synthesis; homologous to bovine subunit OSCP (oligomycin sensitivity-conferring protein); phosphorylated

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    1058176..1058814 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180606.1 → NP_010584.1  TPA: F1F0 ATP synthase subunit 5 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010584.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VSS7, P09457
    UniProtKB/TrEMBL
    A6ZYP6, B3LFZ7, C7GQU8, C8Z5L0, G2WB36, N1P6U3
    Conserved Domains (1) summary
    pfam00213
    Location:32 → 208
    OSCP; ATP synthase delta (OSCP) subunit
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P09457.1

Gene LinkOut

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