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RPL27B ribosomal 60S subunit protein L27B [ Saccharomyces cerevisiae S288C ]

Gene ID: 852082, updated on 18-Sep-2024

Summary

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Official Symbol
RPL27B
Official Full Name
ribosomal 60S subunit protein L27B
Primary source
SGD:S000002879
Locus tag
YDR471W
See related
AllianceGenome:SGD:S000002879; FungiDB:YDR471W; VEuPathDB:YDR471W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Part of preribosome, large subunit precursor. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 16. Orthologous to human RPL27 (ribosomal protein L27). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See RPL27B in Genome Data Viewer
Location:
chromosome: IV
Exon count:
2
Sequence:
Chromosome: IV; NC_001136.10 (1401770..1402564)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Sdc1p Neighboring gene Ugo1p Neighboring gene ncRNA Neighboring gene TRAPP subunit TRS31

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Lithium Chloride Sensitivity in Yeast and Regulation of Translation. Hajikarimlou M, et al. Int J Mol Sci, 2020 Aug 10. PMID 32785068, Free PMC Article
  2. Quantitative proteomic analysis of ribosomal protein L35b mutant of Saccharomyces cerevisiae. Song YB, et al. Biochim Biophys Acta, 2010 Apr. PMID 19879384
  3. Structural transitions during large ribosomal subunit maturation analyzed by tethered nuclease structure probing in S. cerevisiae. Pöll G, et al. PLoS One, 2017. PMID 28686620, Free PMC Article
  4. Collided ribosomes form a unique structural interface to induce Hel2-driven quality control pathways. Ikeuchi K, et al. EMBO J, 2019 Mar 1. PMID 30609991, Free PMC Article
  5. Unifying fluorescence microscopy and mass spectrometry for studying protein complexes in cells. Deng C, et al. Mol Cell Proteomics, 2009 Jun. PMID 19269952, Free PMC Article

See all (70) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IC
Inferred by Curator
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation IC
Inferred by Curator
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit NAS
Non-traceable Author Statement
more info
 PubMed 
part_of preribosome, large subunit precursor IDA
Inferred from Direct Assay
more info
 PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ribosomal 60S subunit protein L27B
NP_010759.1
  • Ribosomal 60S subunit protein L27B; homologous to mammalian ribosomal protein L27, no bacterial homolog; RPL27B has a paralog, RPL27A, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    1401770..1402564
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180779.1 → NP_010759.1  TPA: ribosomal 60S subunit protein L27B [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010759.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VT95, P0C2H7
    UniProtKB/TrEMBL
    C7GMQ1
    Conserved Domains (2) summary
    COG2163
    Location:1 → 128
    RPL14A; Ribosomal protein L14E/L6E/L27E [Translation, ribosomal structure and biogenesis]
    cl00354
    Location:1 → 136
    KOW; KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0C2H7.1

Gene LinkOut

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