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RPL21A [ Saccharomyces cerevisiae S288C ]

Gene ID: 852489, updated on 8-Sep-2024

Summary

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Official Symbol
RPL21A
Primary source
SGD:S000000395
Locus tag
YBR191W
See related
AllianceGenome:SGD:S000000395; FungiDB:YBR191W; VEuPathDB:YBR191W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
URP1
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in hypotrichosis 12. Orthologous to human RPL21 (ribosomal protein L21). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: II
Exon count:
2
Sequence:
Chromosome: II; NC_001134.8 (606270..607140)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene Ntc20p Neighboring gene ribosomal 40S subunit protein S9B Neighboring gene Rim2p Neighboring gene Med8p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001134.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Yeast single copy gene URP1 is a homolog of rat ribosomal protein gene L21. Jank B, et al. Curr Genet, 1993 Jan. PMID 8428379
  2. A 12.5 kb fragment of the yeast chromosome II contains two adjacent genes encoding ribosomal proteins and six putative new genes, one of which encodes a putative transcriptional factor. Démolis N, et al. Yeast, 1994 Nov. PMID 7871891
  3. Innate immunity to yeast prions: Btn2p and Cur1p curing of the [URE3] prion is prevented by 60S ribosomal protein deficiency or ubiquitin/proteasome system overactivity. Bezsonov EE, et al. Genetics, 2021 Apr 15. PMID 33857305, Free PMC Article
  4. Genome-wide survey of non-essential genes required for slowed DNA synthesis-induced filamentous growth in yeast. Kang CM, et al. Yeast, 2005 Jan 30. PMID 15645503
  5. Ribosomal protein and biogenesis factors affect multiple steps during movement of the Saccharomyces cerevisiae Ty1 retrotransposon. Suresh S, et al. Mob DNA, 2015. PMID 26664557, Free PMC Article

See all (86) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IC
Inferred by Curator
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation IC
Inferred by Curator
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ribosomal 60S subunit protein L21A
NP_009750.1
  • Ribosomal 60S subunit protein L21A; homologous to mammalian ribosomal protein L21, no bacterial homolog; RPL21A has a paralog, RPL21B, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    606270..607140
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178539.1 → NP_009750.1  TPA: ribosomal 60S subunit protein L21A [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009750.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VQI5, Q02753
    UniProtKB/TrEMBL
    A6ZLD1, B3LMX1, D3UET4, G2W9J2, N1P6X8
    Conserved Domains (1) summary
    PTZ00189
    Location:1 → 157
    PTZ00189; 60S ribosomal protein L21; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q02753.1

Gene LinkOut

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