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uncharacterized protein [ Saccharomyces cerevisiae S288C ]

Gene ID: 853028, updated on 18-Sep-2024

Summary

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Official Full Name
uncharacterized protein
Primary source
SGD:S000003359
Locus tag
YGR127W
See related
AllianceGenome:SGD:S000003359; FungiDB:YGR127W; VEuPathDB:YGR127W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to be involved in Golgi organization and protein secretion. Predicted to be active in Golgi apparatus. Orthologous to human TANGO2 (transport and golgi organization 2 homolog). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (746798..747736)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene Vsb1p Neighboring gene uncharacterized protein Neighboring gene Utp8p Neighboring gene Syf2p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dynamical remodeling of the transcriptome during short-term anaerobiosis in Saccharomyces cerevisiae: differential response and role of Msn2 and/or Msn4 and other factors in galactose and glucose media. Lai LC, et al. Mol Cell Biol, 2005 May. PMID 15870279, Free PMC Article
  2. Systematic multi-level analysis of an organelle proteome reveals new peroxisomal functions. Yifrach E, et al. Mol Syst Biol, 2022 Sep. PMID 36164978, Free PMC Article
  3. The yeast FIT2 homologs are necessary to maintain cellular proteostasis and membrane lipid homeostasis. Yap WS, et al. J Cell Sci, 2020 Nov 5. PMID 33033181, Free PMC Article
  4. Meiosis-specific cohesin component, Rec8, promotes the localization of Mps3 SUN domain protein on the nuclear envelope. Bommi JR, et al. Genes Cells, 2019 Jan. PMID 30417519
  5. A Genome-Wide Screen Reveals a Role for the HIR Histone Chaperone Complex in Preventing Mislocalization of Budding Yeast CENP-A. Ciftci-Yilmaz S, et al. Genetics, 2018 Sep. PMID 30012561, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in Golgi organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in biological_process ND
No biological Data available
more info
  
involved_in protein secretion IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in peroxisome IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
uncharacterized protein
NP_011643.1
  • Protein involved in heme trafficking to the nucleus; expression is regulated by Msn2p/Msn4p, indicating possible role in stress response; localizes to cytosol and peroxisomes

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    746798..747736
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181256.1 → NP_011643.1  TPA: uncharacterized protein YGR127W [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011643.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VUQ9, P53275
    UniProtKB/TrEMBL
    A6ZUE1, B3LIA1, C7GUG8, N1P424
    Conserved Domains (1) summary
    COG3332
    Location:1 → 309
    NRDE; Uncharacterized conserved protein, contains NRDE domain [Function unknown]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53275.1

Gene LinkOut

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