IMA5 oligo-1,6-glucosidase IMA5 [Saccharomyces cerevisiae S288C] - Gene

Summary

Gene symbol: IMA5
Gene description: oligo-1,6-glucosidase IMA5
Primary source: FungiDB:YJL216C
Locus tag: YJL216C
See related: SGD:S000003752; AllianceGenome:SGD:S000003752; VEuPathDB:YJL216C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Enables oligo-1,6-glucosidase activity. Involved in disaccharide catabolic process. Human ortholog(s) of this gene implicated in cystinuria. Orthologous to several human genes including SLC3A1 (solute carrier family 3 member 1). [provided by Alliance of Genome Resources, Apr 2022]
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Chromosome X - NC_001142.9 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables alpha-amylase activity	IBA Inferred from Biological aspect of Ancestor more info
enables alpha-glucosidase activity	IEA Inferred from Electronic Annotation more info
enables glucan 1,4-alpha-maltotriohydrolase activity	IBA Inferred from Biological aspect of Ancestor more info
enables hydrolase activity, acting on glycosyl bonds	IEA Inferred from Electronic Annotation more info
enables maltose alpha-glucosidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables oligo-1,6-glucosidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables oligo-1,6-glucosidase activity	IDA Inferred from Direct Assay more info	PubMed
enables oligo-1,6-glucosidase activity	IEA Inferred from Electronic Annotation more info
enables oligo-1,6-glucosidase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables sucrose alpha-glucosidase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
involved_in disaccharide catabolic process	IEA Inferred from Electronic Annotation more info
involved_in disaccharide catabolic process	IGI Inferred from Genetic Interaction more info	PubMed
involved_in maltose catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in maltose metabolic process	IEA Inferred from Electronic Annotation more info
involved_in sucrose catabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

NP_012319.1

Alpha-glucosidase; specificity for isomaltose, maltose, and palatinose, but not alpha-methylglucoside; most distant member of the IMA isomaltase family, but with similar catalytic properties as Ima1p and Ima2p; not required for isomaltose utilization, but Ima5p overexpression allows the ima1 null mutant to grow on isomaltose; can cleave alpha-1,3 linkage of nigerose and turanose and alpha-1,5 linkage of leucrose and is very sensitive to temperature in vitro

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