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AIM24 Aim24p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853543, updated on 1-Aug-2024

Summary

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Gene symbol
AIM24
Gene description
Aim24p
Primary source
FungiDB:YJR080C
Locus tag
YJR080C
See related
SGD:S000003841; AllianceGenome:SGD:S000003841; VEuPathDB:YJR080C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
FMP26
Summary
Involved in inner mitochondrial membrane organization. Is integral component of mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See AIM24 in Genome Data Viewer
Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (580432..581616, complement)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene Mir1p Neighboring gene dioxygenase BNA2 Neighboring gene uncharacterized protein Neighboring gene Eaf6p Neighboring gene Acf4p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001142.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Aim24 stabilizes respiratory chain supercomplexes and is required for efficient respiration. Deckers M, et al. FEBS Lett, 2014 Aug 25. PMID 24928273
  2. Aim24 and MICOS modulate respiratory function, tafazzin-related cardiolipin modification and mitochondrial architecture. Harner ME, et al. Elife, 2014 Jan 1. PMID 24714493, Free PMC Article
  3. A role for Saccharomyces cerevisiae Centrin (Cdc31) in mitochondrial function and biogenesis. Chen L, et al. Mol Microbiol, 2018 Dec. PMID 30251372
  4. MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization. Alkhaja AK, et al. Mol Biol Cell, 2012 Jan. PMID 22114354, Free PMC Article
  5. Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis. Hess DC, et al. PLoS Genet, 2009 Mar. PMID 19300474, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. In conclusion, Aim24 by interacting with the MICOS complex plays a key role in mitochondrial architecture, composition and function.
    Title: Aim24 and MICOS modulate respiratory function, tafazzin-related cardiolipin modification and mitochondrial architecture.
  2. Aim24 has a function in stabilizing the respiratory chain supercomplexes
    Title: Aim24 stabilizes respiratory chain supercomplexes and is required for efficient respiration.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in inner mitochondrial membrane organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in inner mitochondrial membrane organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in mitochondrial inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrial inner membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Aim24p
NP_012614.1
  • Protein with a role in determining mitochondrial architecture; inner membrane protein that interacts physically and genetically with the MICOS complex and is required for its integrity

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    580432..581616 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181738.1 → NP_012614.1  TPA: Aim24p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012614.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B3LQG6, C8ZBM7, D6VWQ0, P47127
    UniProtKB/TrEMBL
    G2WH84
    Conserved Domains (1) summary
    cl00884
    Location:49 → 322
    AIM24; Mitochondrial biogenesis AIM24
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P47127.1

Gene LinkOut

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