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PSG1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 853785, updated on 11-Sep-2024

Summary

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Official Symbol
PSG1
Primary source
SGD:S000001560
Locus tag
YKL077W
See related
AllianceGenome:SGD:S000001560; FungiDB:YKL077W; VEuPathDB:YKL077W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in protein maturation and protein targeting. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: XI
Exon count:
1
Sequence:
Chromosome: XI; NC_001143.9 (291453..292631)

Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene Smy1p Neighboring gene RNA helicase Neighboring gene Aan1p Neighboring gene Mud2p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001143.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Selective inhibition of HER2-positive breast cancer cells by the HIV protease inhibitor nelfinavir. Shim JS, et al. J Natl Cancer Inst, 2012 Oct 17. PMID 23042933, Free PMC Article
  2. PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage Response. Ferrari E, et al. Mol Cell, 2017 Jul 20. PMID 28648781, Free PMC Article
  3. The yeast vacuolar membrane proteome. Wiederhold E, et al. Mol Cell Proteomics, 2009 Feb. PMID 19001347
  4. Srs2 and Sgs1 DNA helicases associate with Mre11 in different subcomplexes following checkpoint activation and CDK1-mediated Srs2 phosphorylation. Chiolo I, et al. Mol Cell Biol, 2005 Jul. PMID 15964827, Free PMC Article
  5. Identifying Interaction Partners of Yeast Protein Disulfide Isomerases Using a Small Thiol-Reactive Cross-Linker: Implications for Secretory Pathway Proteostasis. Freije BJ, et al. Chem Res Toxicol, 2022 Feb 21. PMID 35084835, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Ykl077w (Psg1) physically interacts with Exp1 and can be found in the Golgi and COPI vesicles but does not directly bind Pma1.
    Title: Two novel effectors of trafficking and maturation of the yeast plasma membrane H(+) -ATPase.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in protein maturation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein targeting IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in COPI-coated vesicle membrane IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi lumen IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Psg1p
NP_012846.1
  • Protein that promotes the transport and maturation of Pma1 with Exp1; cleaved specifically by Kex2p; localizes to the Golgi apparatus and to the endoplasmic reticulum in HTP studies

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001143.9 Reference assembly

    Range
    291453..292631
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179643.1 → NP_012846.1  TPA: Psg1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012846.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VXL0, P36081
    UniProtKB/TrEMBL
    A6ZZN9, B3LR14, B5VM79, C7GVN1, C8ZC96, G2WHV5, N1P2A8
    Conserved Domains (1) summary
    pfam14610
    Location:143 → 325
    DUF4448; Protein of unknown function (DUF4448)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P36081.1

Gene LinkOut

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