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VLD1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 854831, updated on 11-Sep-2024

Summary

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Official Symbol
VLD1
Primary source
SGD:S000001453
Locus tag
YIR014W
See related
AllianceGenome:SGD:S000001453; FungiDB:YIR014W; VEuPathDB:YIR014W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in protein-containing complex localization. Located in endoplasmic reticulum and fungal-type vacuole. Part of Dsc E3 ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: IX
Exon count:
1
Sequence:
Chromosome: IX; NC_001141.2 (381086..381814)

Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene Sqt1p Neighboring gene Gat4p Neighboring gene ribonuclease P protein subunit RPR2 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001141.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Ubiquitination of phosphatidylethanolamine in organellar membranes. Sakamaki JI, et al. Mol Cell, 2022 Oct 6. PMID 36044902
  2. The Ume6 regulon coordinates metabolic and meiotic gene expression in yeast. Williams RM, et al. Proc Natl Acad Sci U S A, 2002 Oct 15. PMID 12370439, Free PMC Article
  3. Sorting of a multi-subunit ubiquitin ligase complex in the endolysosome system. Yang X, et al. Elife, 2018 Jan 22. PMID 29355480, Free PMC Article
  4. A split-ubiquitin two-hybrid screen for proteins physically interacting with the yeast amino acid transceptor Gap1 and ammonium transceptor Mep2. Van Zeebroeck G, et al. PLoS One, 2011. PMID 21912684, Free PMC Article
  5. The yeast FIT2 homologs are necessary to maintain cellular proteostasis and membrane lipid homeostasis. Yap WS, et al. J Cell Sci, 2020 Nov 5. PMID 33033181, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
part_of Dsc E3 ubiquitin ligase complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in endoplasmic reticulum HDA PubMed 
located_in fungal-type vacuole HDA PubMed 
located_in fungal-type vacuole membrane ISM
Inferred from Sequence Model
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in vacuolar membrane IEA
Inferred from Electronic Annotation
more info
  
located_in vacuole IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Vld1p
NP_012279.4
  • Component of Dsc E3 ligase complex in vacuolar membranes; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; expression directly regulated by the metabolic and meiotic transcriptional regulator Ume6p; YIR014W is a non-essential gene

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001141.2 Reference assembly

    Range
    381086..381814
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179536.3 → NP_012279.4  TPA: Vld1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012279.4

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VVU4, P40570
    UniProtKB/TrEMBL
    A6ZVT3, B3LTJ5, C7GJF8, N1P0R1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P40570.2

Gene LinkOut

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