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uncharacterized protein [ Saccharomyces cerevisiae S288C ]

Gene ID: 855109, updated on 2-Nov-2024

Summary

Official Full Name
uncharacterized protein
Primary source
SGD:S000004690
Locus tag
YMR085W
See related
AllianceGenome:SGD:S000004690; FungiDB:YMR085W; VEuPathDB:YMR085W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable glutamine-fructose-6-phosphate transaminase (isomerizing) activity. Predicted to be involved in several processes, including UDP-N-acetylglucosamine metabolic process; chitin biosynthetic process; and protein N-linked glycosylation. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 12 and obesity. Orthologous to human GFPT1 (glutamine--fructose-6-phosphate transaminase 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (437491..438789)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene alcohol dehydrogenase ADH3 Neighboring gene putative glutamine--fructose-6-phosphate transaminase Neighboring gene Seg1p Neighboring gene putative ADP-ribose 1''-phosphate phosphatase

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables carbohydrate derivative binding IEA
Inferred from Electronic Annotation
more info
 
enables glutamine-fructose-6-phosphate transaminase (isomerizing) activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in UDP-N-acetylglucosamine metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in biological_process ND
No biological Data available
more info
 
involved_in carbohydrate derivative metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in chitin biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in fructose 6-phosphate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein N-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
uncharacterized protein
NP_013802.1
  • hypothetical protein; YMR085W and adjacent ORF YMR084W are merged in related strains, and together are paralogous to glutamine-fructose-6-phosphate amidotransferase GFA1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    437491..438789
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182584.1NP_013802.1  TPA: uncharacterized protein YMR085W [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013802.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    C8ZET8, D6VZQ8, P0CF18
    UniProtKB/TrEMBL
    G2WKD2
    Conserved Domains (1) summary
    COG0449
    Location:2428
    GlmS; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains [Cell wall/membrane/envelope biogenesis]