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PGA2 Pga2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855573, updated on 1-Aug-2024

Summary

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Gene symbol
PGA2
Gene description
Pga2p
Primary source
FungiDB:YNL149C
Locus tag
YNL149C
See related
SGD:S000005093; AllianceGenome:SGD:S000005093; VEuPathDB:YNL149C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in protein transport. Located in endoplasmic reticulum and nuclear envelope. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See PGA2 in Genome Data Viewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (349367..349756, complement)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Inn1p Neighboring gene DNA-directed RNA polymerase III subunit C31 Neighboring gene Alf1p Neighboring gene Sm-like protein LSM7

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001146.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A survey of essential gene function in the yeast cell division cycle. Yu L, et al. Mol Biol Cell, 2006 Nov. PMID 16943325, Free PMC Article
  2. Members of the RSC chromatin-remodeling complex are required for maintaining proper nuclear envelope structure and pore complex localization. Titus LC, et al. Mol Biol Cell, 2010 Mar 15. PMID 20110349, Free PMC Article
  3. ATP synthase interactome analysis identifies a new subunit l as a modulator of permeability transition pore in yeast. Panja C, et al. Sci Rep, 2023 Mar 7. PMID 36882574, Free PMC Article
  4. Heme, A Metabolic Sensor, Directly Regulates the Activity of the KDM4 Histone Demethylase Family and Their Interactions with Partner Proteins. Konduri PC, et al. Cells, 2020 Mar 22. PMID 32235736, Free PMC Article
  5. Assigning function to yeast proteins by integration of technologies. Hazbun TR, et al. Mol Cell, 2003 Dec. PMID 14690591

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in protein transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in protein transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum HDA PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in nuclear envelope HDA PubMed 
located_in nuclear membrane IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Pga2p
NP_014250.1
  • Essential protein required for maturation of Gas1p and Pho8p; involved in protein trafficking; GFP-fusion protein localizes to the ER and YFP-fusion protein to the nuclear envelope-ER network; null mutants have a cell separation defect

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    349367..349756 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182987.1 → NP_014250.1  TPA: Pga2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014250.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W133, P53903
    UniProtKB/TrEMBL
    A6ZRT4, B3LP05, C7GXV0, C8ZG79, G2WLV7, N1NWH5
    Conserved Domains (1) summary
    pfam07543
    Location:16 → 128
    PGA2; Protein trafficking PGA2
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53903.3

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