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MTQ1 S-adenosylmethionine-dependent methyltransferase [ Saccharomyces cerevisiae S288C ]

Gene ID: 855662, updated on 1-Aug-2024

Summary

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Gene symbol
MTQ1
Gene description
S-adenosylmethionine-dependent methyltransferase
Primary source
FungiDB:YNL063W
Locus tag
YNL063W
See related
SGD:S000005007; AllianceGenome:SGD:S000005007; VEuPathDB:YNL063W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables S-adenosylmethionine-dependent methyltransferase activity. Involved in translational readthrough. Located in mitochondrion. Orthologous to human HEMK1 (HemK methyltransferase family member 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See MTQ1 in Genome Data Viewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (507758..508702)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Aqr1p Neighboring gene type I HSP40 co-chaperone YDJ1 Neighboring gene tRNA 1-methyladenosine methyltransferase subunit GCD10 Neighboring gene rRNA (cytosine-C5-)-methyltransferase NOP2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001146.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The yeast translation release factors Mrf1p and Sup45p (eRF1) are methylated, respectively, by the methyltransferases Mtq1p and Mtq2p. Polevoda B, et al. J Biol Chem, 2006 Feb 3. PMID 16321977
  2. Functional analysis of the hemK gene product involvement in protoporphyrinogen oxidase activity in yeast. Le Guen L, et al. FEMS Microbiol Lett, 1999 Apr 1. PMID 10220893
  3. The yeast protein Mam33 functions in the assembly of the mitochondrial ribosome. Hillman GA, et al. J Biol Chem, 2019 Jun 21. PMID 31053642, Free PMC Article
  4. Genome-wide bimolecular fluorescence complementation analysis of SUMO interactome in yeast. Sung MK, et al. Genome Res, 2013 Apr. PMID 23403034, Free PMC Article
  5. The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications. Philippsen P, et al. Nature, 1997 May 29. PMID 9169873

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables S-adenosylmethionine-dependent methyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables S-adenosylmethionine-dependent methyltransferase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein-(glutamine-N5) methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in methylation IEA
Inferred from Electronic Annotation
more info
  
involved_in translational readthrough IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion HDA PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
S-adenosylmethionine-dependent methyltransferase
NP_014336.1
  • S-adenosylmethionine-dependent methyltransferase; methylates translational release factor Mrf1p; similar to E.coli PrmC; is not an essential gene

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    507758..508702
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182901.1 → NP_014336.1  TPA: S-adenosylmethionine-dependent methyltransferase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014336.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W1B7, P53944
    UniProtKB/TrEMBL
    B3LNS2, C7GLU0, C8ZGG6, N1P4I0
    Conserved Domains (1) summary
    TIGR00536
    Location:1 → 283
    hemK_fam; HemK family putative methylases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53944.1

Gene LinkOut

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