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DSE4 endo-1,3(4)-beta-glucanase [ Saccharomyces cerevisiae S288C ]

Gene ID: 855804, updated on 29-Jun-2024

Summary

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Gene symbol
DSE4
Gene description
endo-1,3(4)-beta-glucanase
Primary source
FungiDB:YNR067C
Locus tag
YNR067C
See related
SGD:S000005350; AllianceGenome:SGD:S000005350; VEuPathDB:YNR067C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
ENG1
Summary
Enables glucan endo-1,3-beta-D-glucosidase activity. Involved in septum digestion after cytokinesis. Located in cell septum and cellular bud scar. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See DSE4 in Genome Data Viewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (755746..759099, complement)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Bsc5p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001146.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of the CaENG1 gene encoding an endo-1,3-beta-glucanase involved in cell separation in Candida albicans. Esteban PF, et al. Curr Microbiol, 2005 Dec. PMID 16328626
  2. Eng1p, an endo-1,3-beta-glucanase localized at the daughter side of the septum, is involved in cell separation in Saccharomyces cerevisiae. Baladrón V, et al. Eukaryot Cell, 2002 Oct. PMID 12455695, Free PMC Article
  3. GPI7 involved in glycosylphosphatidylinositol biosynthesis is essential for yeast cell separation. Fujita M, et al. J Biol Chem, 2004 Dec 10. PMID 15452134
  4. Cellular localization of Sun4p and its interaction with proteins in the yeast birth scar. Kuznetsov E, et al. Cell Cycle, 2016 Jul 17. PMID 27229769, Free PMC Article
  5. Disruption of LRG1 inhibits mother-daughter separation in Saccharomyces cerevisiae. Svarovsky MJ, et al. Yeast, 2005 Oct 30. PMID 16240460

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables glucan endo-1,3-beta-D-glucosidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glucan endo-1,3-beta-D-glucosidase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group IEA
Inferred from Electronic Annotation
more info
  
enables glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group IEA
Inferred from Electronic Annotation
more info
  
enables glucosidase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity, acting on glycosyl bonds IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cell wall organization IEA
Inferred from Electronic Annotation
more info
  
involved_in polysaccharide catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in septum digestion after cytokinesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cell septum IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cell surface IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cellular bud neck HDA PubMed 
located_in cellular bud scar IDA
Inferred from Direct Assay
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in fungal-type cell wall IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
endo-1,3(4)-beta-glucanase
NP_014465.1
  • Daughter cell-specific secreted protein with similarity to glucanases; degrades cell wall from the daughter side causing daughter to separate from mother

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    755746..759099 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183244.1 → NP_014465.1  TPA: endo-1,3(4)-beta-glucanase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014465.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W1P2, P53753
    UniProtKB/TrEMBL
    A0A8H4F996, B5VR92, C7GM65
    Conserved Domains (1) summary
    COG5498
    Location:406 → 1117
    Acf2; Endoglucanase Acf2 [Carbohydrate transport and metabolism]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53753.1

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