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MAN2 [ Saccharomyces cerevisiae S288C ]

Gene ID: 855810, updated on 11-Sep-2024

Summary

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Official Symbol
MAN2
Primary source
SGD:S000005356
Locus tag
YNR073C
See related
AllianceGenome:SGD:S000005356; FungiDB:YNR073C; VEuPathDB:YNR073C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables mannitol dehydrogenase activity. Predicted to be involved in mannitol metabolic process. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (774792..776300, complement)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene aldose 1-epimerase superfamily protein Neighboring gene hexose transporter HXT17 Neighboring gene Aif1p Neighboring gene Cos10p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001146.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sequencing of a 9.2 kb telomeric fragment from the right arm of Saccharomyces cerevisiae chromosome XIV. Levesque H, et al. Yeast, 1996 Mar 15. PMID 8904342
  2. Hxt13, Hxt15, Hxt16 and Hxt17 from Saccharomyces cerevisiae represent a novel type of polyol transporters. Jordan P, et al. Sci Rep, 2016 Mar 21. PMID 26996892, Free PMC Article
  3. Cdc1p is a Golgi-localized glycosylphosphatidylinositol-anchored protein remodelase. Yang G, et al. Mol Biol Cell, 2020 Dec 15. PMID 33112703, Free PMC Article
  4. Variation in gene duplicates with low synonymous divergence in Saccharomyces cerevisiae relative to Caenorhabditis elegans. Katju V, et al. Genome Biol, 2009. PMID 19594930, Free PMC Article
  5. Yeast Saccharomyces cerevisiae adiponectin receptor homolog Izh2 is involved in the regulation of zinc, phospholipid and pH homeostasis. Mattiazzi Ušaj M, et al. Metallomics, 2015 Sep. PMID 26067383

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables mannitol 2-dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
  
enables mannitol dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables mannitol dehydrogenase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in mannitol metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
putative mannitol dehydrogenase
NP_014471.3
  • Mannitol dehydrogenase; MAN2 has a paralog, DSF1, that arose from a segmental duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    774792..776300 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183250.3 → NP_014471.3  TPA: putative mannitol dehydrogenase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014471.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DLI1, P0CX08, P0CX09, P39941
    UniProtKB/TrEMBL
    A6ZSE7, B3LPH1, B3LRV0, B5VH68, C8ZFV0
    Conserved Domains (1) summary
    COG0246
    Location:21 → 498
    MtlD; Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0CX08.1
P0CX09.1

Gene LinkOut

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Other Literature Sources
Molecular Biology Databases
Research Materials