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UIP4 Uip4p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855916, updated on 18-Sep-2024

Summary

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Official Symbol
UIP4
Official Full Name
Uip4p
Primary source
SGD:S000006107
Locus tag
YPL186C
See related
AllianceGenome:SGD:S000006107; FungiDB:YPL186C; VEuPathDB:YPL186C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Located in endoplasmic reticulum and nuclear envelope. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See UIP4 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (194512..195426, complement)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene NADH kinase Neighboring gene Mf(Alpha)1p Neighboring gene Mrn1p Neighboring gene putative mitochondrial 54S ribosomal protein RTC6

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001148.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Uip4p modulates nuclear pore complex function in Saccharomyces cerevisiae. Deolal P, et al. Nucleus, 2022 Dec. PMID 35171083, Free PMC Article
  2. Yeast Ulp1, an Smt3-specific protease, associates with nucleoporins. Takahashi Y, et al. J Biochem, 2000 Nov. PMID 11056382
  3. Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Reinders J, et al. Mol Cell Proteomics, 2007 Nov. PMID 17761666
  4. Pex35 is a regulator of peroxisome abundance. Yofe I, et al. J Cell Sci, 2017 Feb 15. PMID 28049721, Free PMC Article
  5. Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins. Zahedi RP, et al. Mol Biol Cell, 2006 Mar. PMID 16407407, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within nuclear envelope organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum HDA PubMed 
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial outer membrane HDA PubMed 
located_in mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
located_in nuclear envelope IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nuclear envelope IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Uip4p
NP_015138.1
  • Protein required for nuclear envelope integrity; involved in distribution of nuclear pore complexes; interacts with Ulp1p, a Ubl (ubiquitin-like protein)-specific protease for Smt3p protein conjugates; detected in a phosphorylated state in the mitochondrial outer membrane; also detected in ER and nuclear envelope

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    194512..195426 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184000.1 → NP_015138.1  TPA: Uip4p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015138.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W3I3, Q08926
    UniProtKB/TrEMBL
    A6ZW68, B3LKP3, B5VSY9, C8ZIJ2, N1NVN8
    Conserved Domains (2) summary
    cd02859
    Location:1 → 87
    E_set_AMPKbeta_like_N; N-terminal Early set domain, a glycogen binding domain, associated with the catalytic domain of AMP-activated protein kinase beta subunit
    COG5271
    Location:73 → 271
    MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q08926.1

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