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SPC29 Spc29p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855979, updated on 2-Nov-2024

Summary

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Official Symbol
SPC29
Official Full Name
Spc29p
Primary source
SGD:S000006045
Locus tag
YPL124W
See related
AllianceGenome:SGD:S000006045; FungiDB:YPL124W; VEuPathDB:YPL124W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
LPH3; NIP29
Summary
Predicted to be a structural constituent of cytoskeleton. Involved in mitotic spindle pole body duplication. Located in spindle pole body. Is active in central plaque of mitotic spindle pole body. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See SPC29 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (316755..317516)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Nan1p Neighboring gene Kap120p Neighboring gene ribonuclease T2 Neighboring gene TFIIH/NER complex subunit TFB2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001148.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Budding yeast centrosome duplication requires stabilization of Spc29 via Mps1-mediated phosphorylation. Holinger EP, et al. J Biol Chem, 2009 May 8. PMID 19269975, Free PMC Article
  2. Phosphorylation and spindle pole body localization of the Cdc15p mitotic regulatory protein kinase in budding yeast. Xu S, et al. Curr Biol, 2000 Mar 23. PMID 10744974
  3. Analysis of coiled-coil interactions between core proteins of the spindle pole body. Zizlsperger N, et al. Biochemistry, 2008 Nov 11. PMID 18850724
  4. The N-terminus of Sfi1 and yeast centrin Cdc31 provide the assembly site for a new spindle pole body. Rüthnick D, et al. J Cell Biol, 2021 Mar 1. PMID 33523111, Free PMC Article
  5. Yeast pericentrin/Spc110 contains multiple domains required for tethering the γ-tubulin complex to the centrosome. Alonso A, et al. Mol Biol Cell, 2020 Jul 1. PMID 32374651, Free PMC Article

See all (59) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables structural constituent of cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in mitotic spindle pole body duplication IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in spindle pole body duplication IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in central plaque of mitotic spindle pole body IDA
Inferred from Direct Assay
more info
 PubMed 
located_in central plaque of spindle pole body IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in spindle pole body HDA PubMed 
located_in spindle pole body IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Spc29p
NP_015201.1
  • Inner plaque spindle pole body (SPB) component; links the central plaque component Spc42p to the inner plaque component Spc110p; required for SPB duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    316755..317516
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183938.1 → NP_015201.1  TPA: Spc29p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015201.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B3LKV0, B5VT41, C7GJ78, C8ZIQ5, D6W3P3, E7KVI3, E7M1C7, E7QLB7, P33419
    UniProtKB/TrEMBL
    N1NVV8
    Conserved Domains (1) summary
    pfam17082
    Location:1 → 251
    Spc29; Spindle Pole Component 29
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P33419.1

Gene LinkOut

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