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PEX25 Pex25p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855991, updated on 18-Sep-2024

Summary

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Official Symbol
PEX25
Official Full Name
Pex25p
Primary source
SGD:S000006033
Locus tag
YPL112C
See related
AllianceGenome:SGD:S000006033; FungiDB:YPL112C; VEuPathDB:YPL112C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in protein import into peroxisome matrix. Located in peroxisomal membrane. Colocalizes with peroxisome. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See PEX25 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (337436..338620, complement)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene GTPase-activating protein BEM3 Neighboring gene glyoxylate reductase Neighboring gene tRNA-Met Neighboring gene arginase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001148.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Increased peroxisome proliferation is associated with early yeast replicative ageing. Deb R, et al. Curr Genet, 2022 Apr. PMID 35220444
  2. A combined approach of quantitative interaction proteomics and live-cell imaging reveals a regulatory role for endoplasmic reticulum (ER) reticulon homology proteins in peroxisome biogenesis. David C, et al. Mol Cell Proteomics, 2013 Sep. PMID 23689284, Free PMC Article
  3. A subtle interplay between three Pex11 proteins shapes de novo formation and fission of peroxisomes. Huber A, et al. Traffic, 2012 Jan. PMID 21951626, Free PMC Article
  4. Conserved function of pex11p and the novel pex25p and pex27p in peroxisome biogenesis. Rottensteiner H, et al. Mol Biol Cell, 2003 Oct. PMID 14517338, Free PMC Article
  5. Pex11-related proteins in peroxisome dynamics: a role for the novel peroxin Pex27p in controlling peroxisome size and number in Saccharomyces cerevisiae. Tam YY, et al. Mol Biol Cell, 2003 Oct. PMID 14517321, Free PMC Article

See all (45) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in peroxisome fission IEA
Inferred from Electronic Annotation
more info
  
involved_in peroxisome organization IEA
Inferred from Electronic Annotation
more info
  
involved_in peroxisome organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein import into peroxisome matrix IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in peroxisomal membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in peroxisomal membrane IEA
Inferred from Electronic Annotation
more info
  
located_in peroxisome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Pex25p
NP_015213.1
  • Peripheral peroxisomal membrane peroxin; required for the regulation of peroxisome size and maintenance, recruits GTPase Rho1p to peroxisomes, induced by oleate, interacts with Pex27p; PEX25 has a paralog, PEX27, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    337436..338620 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183926.1 → NP_015213.1  TPA: Pex25p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015213.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W3Q5, Q02969, Q6B2A9
    UniProtKB/TrEMBL
    B3LKW1, C7GJ66, C8ZIR8, G2WP69, N1P1J7
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q02969.1

Gene LinkOut

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