ATP4 [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: ATP4
Primary source: SGD:S000005999
Locus tag: YPL078C
See related: AllianceGenome:SGD:S000005999; FungiDB:YPL078C; VEuPathDB:YPL078C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as: LPF7
Summary: Contributes to proton-transporting ATP synthase activity, rotational mechanism and proton-transporting ATPase activity, rotational mechanism. Involved in ATP synthesis coupled proton transport and protein-containing complex assembly. Located in mitochondrion. Part of mitochondrial proton-transporting ATP synthase, stator stalk. Orthologous to human ATP5PB (ATP synthase peripheral stalk-membrane subunit b). [provided by Alliance of Genome Resources, Apr 2022]
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Chromosome XVI - NC_001148.4 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables proton transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
contributes_to proton-transporting ATP synthase activity, rotational mechanism	IBA Inferred from Biological aspect of Ancestor more info
contributes_to proton-transporting ATP synthase activity, rotational mechanism	IDA Inferred from Direct Assay more info	PubMed
contributes_to proton-transporting ATPase activity, rotational mechanism	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
involved_in protein-containing complex assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in proton motive force-driven ATP synthesis	IBA Inferred from Biological aspect of Ancestor more info
involved_in proton motive force-driven ATP synthesis	IDA Inferred from Direct Assay more info	PubMed
involved_in proton motive force-driven ATP synthesis	IEA Inferred from Electronic Annotation more info
involved_in proton motive force-driven ATP synthesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in proton transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
part_of mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)	IBA Inferred from Biological aspect of Ancestor more info
part_of mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	HDA more info	PubMed
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrion	IMP Inferred from Mutant Phenotype more info	PubMed
part_of proton-transporting ATP synthase complex, coupling factor F(o)	IEA Inferred from Electronic Annotation more info
part_of proton-transporting ATP synthase, stator stalk	IDA Inferred from Direct Assay more info	PubMed

NP_015247.1

Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase; ATP synthase is a large, evolutionarily conserved enzyme complex required for ATP synthesis; contributes to the oligomerization of the complex, which in turn determines the shape of inner membrane cristae; phosphorylated

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The following sections contain reference sequences that belong to a specific genome build. Explain