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UBP16 [ Saccharomyces cerevisiae S288C ]

Gene ID: 856032, updated on 11-Sep-2024

Summary

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Official Symbol
UBP16
Primary source
SGD:S000005993
Locus tag
YPL072W
See related
AllianceGenome:SGD:S000005993; FungiDB:YPL072W; VEuPathDB:YPL072W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable thiol-dependent deubiquitinase. Predicted to be involved in protein deubiquitination. Located in mitochondrial outer membrane. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (418512..420011)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene transcription regulator GCR1 Neighboring gene putative AAA family ATPase YTA6 Neighboring gene uncharacterized protein Neighboring gene guanine nucleotide exchange factor MUK1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001148.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The yeast deubiquitinating enzyme Ubp16 is anchored to the outer mitochondrial membrane. Kinner A, et al. FEBS Lett, 2003 Aug 14. PMID 12914939
  2. Ubiquitin-dependent protein degradation. Hochstrasser M. Annu Rev Genet, 1996. PMID 8982460
  3. Analysis of the deubiquitinating enzymes of the yeast Saccharomyces cerevisiae. Amerik AY, et al. Biol Chem, 2000 Sep-Oct. PMID 11076031
  4. Genetic interactions of a putative Arabidopsis thaliana ubiquitin-ligase with components of the Saccharomyces cerevisiae ubiquitination machinery. Aguilar-Henonin L, et al. Curr Genet, 2006 Oct. PMID 16897085
  5. Identification of deubiquitinating enzymes involved in methylmercury toxicity in Saccharomyces cerevisiae. Hwang GW, et al. J Toxicol Sci, 2012. PMID 23208446

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
  
enables cysteine-type deubiquitinase activity TAS
Traceable Author Statement
more info
 PubMed 
enables cysteine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein deubiquitination IEA
Inferred from Electronic Annotation
more info
  
involved_in protein deubiquitination TAS
Traceable Author Statement
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrial outer membrane HDA PubMed 
located_in mitochondrial outer membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion HDA PubMed 

General protein information

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Preferred Names
putative ubiquitin-specific protease UBP16
NP_015253.1
  • Putative deubiquitinating enzyme anchored to the outer mitochondrial membrane; probably not important for general mitochondrial functioning, but may perform a more specialized function at mitochondria

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    418512..420011
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183886.1 → NP_015253.1  TPA: putative ubiquitin-specific protease UBP16 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015253.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W3U3, Q02863
    UniProtKB/TrEMBL
    A6ZWH7, B3LKZ7, B5VT91, C7GTY5, N1P1P1
    Conserved Domains (1) summary
    cd02662
    Location:54 → 495
    Peptidase_C19F; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q02863.1

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