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SOM1 Som1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 856650, updated on 18-Sep-2024

Summary

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Official Symbol
SOM1
Official Full Name
Som1p
Primary source
SGD:S000002954
Locus tag
YEL059C-A
See related
AllianceGenome:SGD:S000002954; FungiDB:YEL059C-A; VEuPathDB:YEL059C-A
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to contribute to endopeptidase activity. Involved in mitochondrial respiratory chain complex assembly and proteolysis. Located in mitochondrial inner membrane. Part of mitochondrial inner membrane peptidase complex. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See SOM1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
1
Sequence:
Chromosome: V; NC_001137.3 (42400..42624, complement)

Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene kinesin motor protein CIN8 Neighboring gene proteinase B Neighboring gene Hhy1p Neighboring gene phosphoacetylglucosamine mutase PCM1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001137.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Saccharomyces cerevisiae SOM1 gene: heterologous complementation studies, homologues in other organisms, and association of the gene product with the inner mitochondrial membrane. Bauerfeind M, et al. Mol Gen Genet, 1998 Apr. PMID 9604886
  2. SOM 1, a small new gene required for mitochondrial inner membrane peptidase function in Saccharomyces cerevisiae. Esser K, et al. Mol Gen Genet, 1996 Sep 25. PMID 8879245
  3. Cargo sequences are important for Som1p-dependent signal peptide cleavage in yeast mitochondria. Liang H, et al. J Biol Chem, 2004 Sep 17. PMID 15254042
  4. Som1, a third component of the yeast mitochondrial inner membrane peptidase complex that contains Imp1 and Imp2. Jan PS, et al. Mol Gen Genet, 2000 Apr. PMID 10821182
  5. The mitochondrial IMP peptidase of yeast: functional analysis of domains and identification of Gut2 as a new natural substrate. Esser K, et al. Mol Genet Genomics, 2004 Jun. PMID 15118906

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
contributes_to endopeptidase activity IC
Inferred by Curator
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitochondrial respiratory chain complex assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
part_of mitochondrial inner membrane peptidase complex IEA
Inferred from Electronic Annotation
more info
  
part_of mitochondrial inner membrane peptidase complex IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Som1p
NP_058154.3
  • Subunit of the mitochondrial inner membrane peptidase (IMP); IMP is required for maturation of mitochondrial proteins of the intermembrane space; Som1p facilitates cleavage of a subset of substrates; contains twin cysteine-x9-cysteine motifs

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001137.3 Reference assembly

    Range
    42400..42624 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180854.3 → NP_058154.3  TPA: Som1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_058154.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DLJ1, Q05676
    UniProtKB/TrEMBL
    A6ZQP2, B3LRV9, C7GXE6, C8Z6T2, G2WCH5, N1P578
    Conserved Domains (1) summary
    pfam11093
    Location:1 → 69
    Mitochondr_Som1; Mitochondrial export protein Som1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q05676.1

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