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NOP16 Nop16p [ Saccharomyces cerevisiae S288C ]

Gene ID: 856719, updated on 1-Aug-2024

Summary

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Gene symbol
NOP16
Gene description
Nop16p
Primary source
FungiDB:YER002W
Locus tag
YER002W
See related
SGD:S000000804; AllianceGenome:SGD:S000000804; VEuPathDB:YER002W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in ribosomal large subunit biogenesis. Located in nucleolus. Part of preribosome, large subunit precursor. Orthologous to human NOP16 (NOP16 nucleolar protein). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See NOP16 in Genome Data Viewer
Location:
chromosome: V
Exon count:
1
Sequence:
Chromosome: V; NC_001137.3 (156803..157498)

Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene Irc22p Neighboring gene alpha-1,3-mannosyltransferase MNN1 Neighboring gene mannose-6-phosphate isomerase PMI40 Neighboring gene Fmp52p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001137.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mak5 and Ebp2 act together on early pre-60S particles and their reduced functionality bypasses the requirement for the essential pre-60S factor Nsa1. Pratte D, et al. PLoS One, 2013. PMID 24312670, Free PMC Article
  2. Ytm1, Nop7, and Erb1 form a complex necessary for maturation of yeast 66S preribosomes. Miles TD, et al. Mol Cell Biol, 2005 Dec. PMID 16287855, Free PMC Article
  3. Modular assembly of the nucleolar pre-60S ribosomal subunit. Sanghai ZA, et al. Nature, 2018 Apr 5. PMID 29512650, Free PMC Article
  4. A catabolic block does not sufficiently explain how 2-deoxy-D-glucose inhibits cell growth. Ralser M, et al. Proc Natl Acad Sci U S A, 2008 Nov 18. PMID 19004802, Free PMC Article
  5. The molecular basis for ANE syndrome revealed by the large ribosomal subunit processome interactome. McCann KL, et al. Elife, 2016 Apr 14. PMID 27077951, Free PMC Article

See all (79) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in ribosomal large subunit biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosomal large subunit biogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus HDA PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of preribosome, large subunit precursor HDA PubMed 
part_of preribosome, large subunit precursor IDA
Inferred from Direct Assay
more info
 PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Nop16p
NP_010917.3
  • Constituent of 66S pre-ribosomal particles; involved in 60S ribosomal subunit biogenesis

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001137.3 Reference assembly

    Range
    156803..157498
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178893.3 → NP_010917.3  TPA: Nop16p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010917.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DLP8, P40007
    UniProtKB/TrEMBL
    B3LS13, B5VHD3, C8Z700, N1P3W4
    Conserved Domains (1) summary
    pfam09420
    Location:5 → 222
    Nop16; Ribosome biogenesis protein Nop16
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P40007.1

Gene LinkOut

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