TRP2 anthranilate synthase TRP2 [Saccharomyces cerevisiae S288C] - Gene

Summary

Go to the top of the page Help

Official Symbol: TRP2
Official Full Name: anthranilate synthase TRP2
Primary source: SGD:S000000892
Locus tag: YER090W
See related: AllianceGenome:SGD:S000000892; FungiDB:YER090W; VEuPathDB:YER090W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Enables anthranilate synthase activity. Involved in tryptophan biosynthetic process. Located in cytoplasm. Part of anthranilate synthase complex. [provided by Alliance of Genome Resources, Nov 2024]
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See TRP2 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 1

Sequence:: Chromosome: V; NC_001137.3 (337949..339472)

Chromosome V - NC_001137.3 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_001137.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Homology

Orthologs from OrthoDB

Gene Ontology Provided by SGD

Function	Evidence Code	Pubs
enables anthranilate synthase activity	IDA Inferred from Direct Assay more info	PubMed
enables anthranilate synthase activity	IEA Inferred from Electronic Annotation more info
enables anthranilate synthase activity	IGI Inferred from Genetic Interaction more info	PubMed
enables lyase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in tryptophan biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in tryptophan biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in tryptophan biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of anthranilate synthase complex	IPI Inferred from Physical Interaction more info	PubMed
located_in cytoplasm	HDA more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: anthranilate synthase TRP2

NP_011014.1

EC 4.1.3.27

Anthranilate synthase; catalyzes the initial step of tryptophan biosynthesis, forms multifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp3p

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_001137.3 Reference assembly

Range

337949..339472

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001178981.1 → NP_011014.1 TPA: anthranilate synthase TRP2 [Saccharomyces cerevisiae S288C]

See identical proteins and their annotated locations for NP_011014.1

Status: REVIEWED

UniProtKB/Swiss-Prot

D3DLZ7, P00899

UniProtKB/TrEMBL

B3LRK8, B5VHL7, C7GRS3, C8Z7A6, G2WCY1

Conserved Domains (1) summary

TIGR00564
Location:37 → 494

trpE_most; anthranilate synthase component I, non-proteobacterial lineages